Eugenol manufacturers and suppliers

Eugenol suppliers

Properties

Melting point:: -12--10 °C (lit.)

Boiling point:: 254 °C (lit.)

Density: 1.067 g/mL at 25 °C (lit.)

vapor pressure: <0.1 hPa (25 °C)

refractive index: n20/D 1.541(lit.)

FEMA: 2467 | EUGENOL

Flash point:: >230 °F

storage temp.: 2-8°C

solubility: 2.46g/l

pka: pKa 9.8 (Uncertain)

form: Liquid

color: Clear pale yellow to yellow

Odor: at 10.00 % in dipropylene glycol. sweet spicy clove woody

Odor Type: spicy

biological source: synthetic

Water Solubility: slightly soluble

Sensitive: Air Sensitive

Merck: 14,3898

JECFA Number: 1529

BRN: 1366759

Henry's Law Constant: 9.2×10⁰ mol/(m³Pa) at 25℃, McFall et al. (2020)

Dielectric constant: 6.1（18℃）

Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.

Major Application: agriculture
cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

Cosmetics Ingredients Functions: DENATURANT
TONIC
PERFUMING

InChI: 1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3

InChIKey: RRAFCDWBNXTKKO-UHFFFAOYSA-N

SMILES: COc1cc(CC=C)ccc1O

LogP: 1.83 at 30℃

CAS DataBase Reference: 97-53-0(CAS DataBase Reference)

IARC: 3 (Vol. 36, Sup 7) 1987

NIST Chemistry Reference: Eugenol(97-53-0)

EPA Substance Registry System: Eugenol (97-53-0)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H317-H319

Precautionary statements: P261-P264-P272-P280-P302+P352-P305+P351+P338

PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes: Xn,Xi

Risk Statements: 22-36/37/38-42/43-38-40-43-36/38

Safety Statements: 26-36-24/25-23-36/37

RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany: 1

RTECS: SJ4375000

F: 10-23

TSCA: TSCA listed

HS Code: 29095090

Storage Class: 10 - Combustible liquids

Hazard Classifications: Eye Irrit. 2
Skin Sens. 1

Hazardous Substances Data: 97-53-0(Hazardous Substances Data)

Toxicity: LD50 in rats, mice (mg/kg): 2680, 3000 orally (Hagan)

REACH Registrations: Active

Use

Eugenol has a strong bactericidal and local anti-corrosive effect. It could be used for dental caries as a local analgesic drug. Eugenol is an intermediate of some other spices. Derivatives are eugenol, methyl eugenol, methyl isobutyl eugenol, acetylbutanoic eugenol, acetyl tauer eugenol, and benzyl isobornylphenol. When the eugenol is heated in potassium hydroxide, the double bond of propenyl is rearranged to form -propenyl conjugated to the benzene ring to obtain isobutanol. Then acetylation and mild oxidation of isobutanol and -propenyl cleavage is carried out. Finally we get vanillin, which is the main ingredient of an important artificial flavoring. Eugenol can also be used to prepare isonicid that is the specific drug for treatment of tuberculosis. It also could lower blood pressure.

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