Lupeol manufacturers and suppliers

Lupeol suppliers

Properties

Melting point:: 215°

alpha: D20 +27.2° (c = 4.8 in chloroform)

Boiling point:: 482.1°C (rough estimate)

Density: 0.9457

refractive index: 1.4910 (estimate)

storage temp.: 2-8°C

solubility: Chloroform (Slightly), Methanol (Slightly)

pka: 15.19±0.70(Predicted)

form: Solid

color: White to Off-White

optical activity: +26.420 (c 3.51, CHCl3)

Cosmetics Ingredients Functions: SKIN CONDITIONING

InChIKey: MQYXUWHLBZFQQO-QGTGJCAVSA-N

SMILES: [H]C12CCC3C4(C)CCC(O)C(C)(C)[C@]4([H])CCC3(C)[C@]1(C)CCC5(C)CC[C@H](C(C)=C)[C@]25[H]

LogP: 10.460 (est)

CAS DataBase Reference: 545-47-1(CAS DataBase Reference)

NIST Chemistry Reference: Lupeol(545-47-1)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P501

PPE: Eyeshields, Gloves, type N95 (US)

Safety Statements: 24/25

WGK Germany: 2

RTECS: OK5763000

HS Code: 29061990

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Oral

Hazardous Substances Data: 545-47-1(Hazardous Substances Data)

Use

Lupeol is a kind of novel anti-inflammatory and anti-cancer dietary triterpene that can be found in white cabbage, green pepper, strawberry, olive, mangoes and grapes. In recent years, much progress has been made on the application of this molecule for clinical treatment of various kind of disorders. On the one hand, it has been extensively studied that it is capable of inhibiting inflammation under both in vitro and in animal models. Studies have shown that Lupeol is a multi-target agent during its anti-inflammation effect, targeting on many key molecular pathways involving nuclear factor kappa B (NFB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/-catenin. On the other hand, Lupeol has strong anti-tumor effect during treatment of various cancer types such as prostate, skin, pancreatic and breast cancer. The anti-tumor effect might be related to its potential to modulate important signaling pathways such as nuclear factor kappa B (NFB) and the phosphatidylinositol 3-kinase [PI3K] /Akt (protein kinase B pathway), which are crucial during tumorigenesis.

You can find Lupeol suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.