Pimavanserin suppliers
Pimavanserin
- CAS:
- 706779-91-1
- MF:
- C25H34FN3O2
- MW:
- 427.55
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Properties
- Melting point:
- 100-103oC
- Boiling point:
- 604.2±55.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Methanol (Slightly)
- pka
- 13.52±0.46(Predicted)
- form
- Solid
- color
- Pale Yellow to Pale Orange
- InChI
- InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
- InChIKey
- RKEWSXXUOLRFBX-UHFFFAOYSA-N
- SMILES
- N(CC1=CC=C(F)C=C1)(C1CCN(C)CC1)C(NCC1=CC=C(OCC(C)C)C=C1)=O
- CAS DataBase Reference
- 706779-91-1(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
- Hazard Codes
- Xi
- Safety Statements
- 24/25
- HS Code
- 29339900
Use
Pimavanserin is an atypical antipsychotic which is approved for the treatment of Parkinson's disease psychosis and is also being researched for the treatment of Alzheimer’s disease psychosis, schizophrenia, agitation, and major depressive disorder. Unlike other antipsychotics, pimavanserin is not a dopamine receptor antagonist. Pimavanserin acts as an inverse agonist and antagonist at serotonin 5-HT2A [5] receptors with high binding affinity (Ki 0.087 nM) and at serotonin 5-HT2C receptors with lower binding affinity (Ki 0.44 nM). Pimavanserin shows low binding to σ1 receptors (Ki 120 nM) and has no appreciable affinity (Ki >300 nM) to serotonin 5-HT2B, dopamine (including D2), muscarinic acetylcholine, histamine, or adrenergic receptors, or to calcium channels.
158 supplier list of "Pimavanserin"
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1KG.5KG;25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Upadacitinib,Vonoprazan Fumarate,Cyanocobalamin,Tofacitinib citrate,vitamins
- Product Name:Pimavanserin
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$35.00-0.90 / 1kg
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1kg;35USD|1000kg;0.9USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,pharmaceutical intermediates,Flavors and Fragrances,OLED
- Product Name:Pimavanserin
- Products Intro:Purity: 0.98 | Package: 100KG;10KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
$2.00/ 1kg
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Pimavanserin
- Products Intro:Purity: >=95% | Package: 100 mg | CustNote: Reach out to us for more information about custom solutions.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:pimavanserin
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pimavanserin；ACP-103
- Products Intro:Purity: 98% | Package: 100mg;108USD|25mg;44USD|50mg;68USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Pimavanserin
- Products Intro:Purity: 99.00% | Package: 25kgs/Drum;200kgs/Drum | CustNote: ISO 9001：2015 REACH Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:PIMAVANSERIN
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes