Rizatriptan benzoate manufacturers and suppliers

Rizatriptan benzoate suppliers

Properties

Melting point:: 178-180°C

storage temp.: 2-8°C

solubility: H2O: ≥5mg/mL

form: powder

color: white to beige

Water Solubility: H2O: ≥5mg/mL

Merck: 14,8241

InChIKey: JPRXYLQNJJVCMZ-UHFFFAOYSA-N

CAS DataBase Reference: 145202-66-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H360

Precautionary statements: P201-P308+P313

Hazard Codes: T

Risk Statements: 61

WGK Germany: 3

HS Code: 2933995500

Use

Known as a 5-hydroxytryptamine agonist, Rizatriptan Benzoate is the benzoate salt form of rizatriptan with anti-migraine activity, which can be used to treat the migraine headaches. It is FDA-approved to use in the treatment of acute migraine attacks with or without aura, especially taken at the first sign of a migraine headache. However, it cannot prevent future migraine attacks and it is ineffective to prevent other types of headache. The pain of migraine headaches is believed to be induced by dilated blood vessels inside the head. Rizatriptan Benzoate relieves the pain by inducing vasoconstriction, which functions as an agonist at serotonin 5-HT1B and 5-HT1D receptors. The selective receptor binding is effective to constrict cranial vessels and inhibit the transmission of nociception, thus providing relief of migraine headaches.

You can find Rizatriptan benzoate suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.