T0901317 suppliers
T0901317
- CAS:
- 293754-55-9
- MF:
- C17H12F9NO3S
- MW:
- 481.33
Suppliers by country/region
Company Type
Properties
- Melting point:
- 116-118°C
- Boiling point:
- 470.5±55.0 °C(Predicted)
- Density
- 1.550±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Light beige solid
- pka
- 9.00±0.15(Predicted)
- color
- Off-White
- InChI
- InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
- InChIKey
- SGIWFELWJPNFDH-UHFFFAOYSA-N
- SMILES
- C1(S(N(CC(F)(F)F)C2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)(=O)=O)=CC=CC=C1
Safety Information
- PPE
- Eyeshields, Gloves, type N95 (US)
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
Use
The Liver X Receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7α-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and selective agonist for both LXRα and LXRβ, with an EC50 of about 50 nM. T0901317 acting through LXR and in concert with its RXR heterodimerization partner induces the expression of the ABCA1 reverse cholesterol transporter. This acts to increase the efflux of cholesterol from enterocytes and thus inhibit the overall absorption of cholesterol.
98 supplier list of "T0901317"
$32.00-80.00
- Product Name:T0901317
- Products Intro:Purity: 99.58% | Package: 5mg;32USD|10mg;52USD|25mg;80USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:T0901317
- Products Intro:Purity: 95.0% windy 23
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:T0901317
- Products Intro:Purity: >98% | Package: 300 mg | CustNote: Please reach out to us for more information about custom solutions.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:T0901317
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: T0901317
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:T0901317
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:T0901317
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others
- Product Name:T0901317
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:T0901317
- Products Intro:Purity: >=98% | Package: $29.9/5mg;$49.9/10mg;$75.9/25mg;$95.9/50mg;$149.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:T0901317
- Products Intro:Purity: 98% | Package: 25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical Material,Active Pharm Ingredients,Petroleum Chemical,pharmaceutical intermediates,liquid crystal OLED materials
- Product Name:T0901317
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A876482
- Company Type: Reagent
- Country/Region: CHINA