Triptorelin manufacturers and suppliers

Triptorelin suppliers

Properties

Melting point:: >180°C (dec.)

alpha: D23 -58.8° (c = 0.33 in acetic acid)

Density: 1.52±0.1 g/cm3(Predicted)

storage temp.: -20°C

solubility: Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated)

pka: 9.82±0.15(Predicted)

form: powder

color: White to Off-White

Stability:: Hygroscopic

InChIKey: HPPONSCISKROOD-OYLNGHKZSA-N

CAS DataBase Reference: 57773-63-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H360

Precautionary statements: P201-P308+P313

PPE: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes: T

Risk Statements: 60

Safety Statements: 53-22-36/37/39-45

WGK Germany: 3

HS Code: 2937190000

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Repr. 1B

Use

The active ingredient of triptorelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue, which is also known as decapeptyl, diphereline, triptorelin acetate, gonadorelin. It is an antineoplastic drug, whose pharmacological effects are same with goserelin, buserelin, and its structure is modified by natural molecular structure of the sixth L-glycine that is replaced by D-tryptophan to promote efficiency and prolong the plasmic half-life time, as well as enhance drug efficacy. It Clinically uses for the treatment of endometriosis, hormone-dependent prostate cancer, breast cancer, precocious puberty, as well as it may also be used as assisted reproductive technology. The main side effects of triptorelin are as follows: In the early stage of treatment of male, it can cause urinary disorders, breast swelling and pain, bone pain, and it may also cause hot flashes, loss of libido and impotence. It rarely cause gynecomastia, testicular atrophy, and sleep disorders.

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