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ChemicalBook >> CAS DataBase List >> (S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one price.
  • $28 - $8880
  • Product name: (S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
  • CAS: 1523406-39-4
  • MF: C19H21ClF3N5O2
  • MW: 443.85
  • EINECS:
  • MDL Number:MFCD28411361
  • Synonyms:SAR-405;SAR 405;CS-2552;4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8S)-;(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one;SAR-405;(S)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydr;(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one;(S)-9-((5-Chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
Price47 Properties Safety Information Description
47 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM*1mLinDMSO
  • 500μg
  • 2.5mg
  • 50mg
  • 250mg
  • 1g
  • 1.00g
  • 10mM(in1mLDMSO)
  • 1mg
  • 2mg
  • 25mg
  • 100mg
  • 5MG
  • 10mg
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00ABQG
  • Product description(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 98+%
  • Packaging1mg
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABQG
  • Product description(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 98+%
  • Packaging2mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABQG
  • Product description(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 95%
  • Packaging25mg
  • Price$260
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABQG
  • Product description(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 95%
  • Packaging100mg
  • Price$735
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15702
  • Product descriptionSAR-405 98%
  • Packaging25MG
  • Price$306
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15702
  • Product descriptionSAR-405 98%
  • Packaging5MG
  • Price$86
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15702
  • Product descriptionSAR-405 98%
  • Packaging100MG
  • Price$1161
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3901DW
  • Product descriptionCID72709209
  • Packaging1mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3901DW
  • Product descriptionCID72709209
  • Packaging5mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging25mg
  • Price$465
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging10mg
  • Price$240
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging2mg
  • Price$99
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging10mM(in 1mL DMSO)
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging10mM(in1mLDMSO)
  • Price$127
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging5mg
  • Price$130
  • Updated2026-05-06
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0016
  • Product descriptionSAR405 98%
  • Packaging5mg
  • Price$174
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABQG (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 98+% 1mg $28 2026-05-28 Buy
aablocks AA00ABQG (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 98+% 2mg $41 2026-05-28 Buy
aablocks AA00ABQG (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 95% 25mg $260 2026-05-28 Buy
aablocks AA00ABQG (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one 95% 100mg $735 2026-05-28 Buy
ACHEMBLOCK M15702 SAR-405 98% 25MG $306 2026-05-27 Buy
ACHEMBLOCK M15702 SAR-405 98% 5MG $86 2026-05-27 Buy
ACHEMBLOCK M15702 SAR-405 98% 100MG $1161 2026-05-27 Buy
AK Scientific 3901DW CID72709209 1mg $209 2021-12-16 Buy
AK Scientific 3901DW CID72709209 5mg $313 2021-12-16 Buy
ApexBio Technology A8883 SAR405 25mg $465 2026-05-06 Buy
ApexBio Technology A8883 SAR405 10mg $240 2026-05-06 Buy
ApexBio Technology A8883 SAR405 2mg $99 2026-05-06 Buy
ApexBio Technology A8883 SAR405 10mM(in 1mL DMSO) $127 2021-12-16 Buy
ApexBio Technology A8883 SAR405 10mM(in1mLDMSO) $127 2026-05-06 Buy
ApexBio Technology A8883 SAR405 5mg $130 2026-05-06 Buy
Apolloscientific BISN0016 SAR405 98% 5mg $174 2021-12-16 Buy
Next Last

Properties

Boiling point :526.5±60.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥22.19 mg/mL in DMSO; insoluble in H2O; ≥32.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :3.29±0.20(Predicted)
color :Off-white to light yellow
InChI :1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/m1/s1
InChIKey :SPDQRCUBFSRAFI-DOMZBBRYSA-N
SMILES :FC(F)(F)[C@H]1N(c3[n]([c](cc(n3)N4[C@@H](COCC4)C)=O)CC1)Cc2cncc(c2)Cl

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SAR 405 is an anticancer agent and a phosphoinositide 3-kinase (PI3K) inhibitor.

More related product prices

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one XL-388 OSI-027 REVERSINE BML-275

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Suppliers and manufacturers

Shanghai Aladdin Bio-Chem Technology Co.,LTD ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai Balmxy Pharmaceutical Co., Ltd Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Beijing Solarbio Science & Tecnology Co., Ltd. Amadis Chemical Company Limited Dezhou LonWel Pharmaceutical Technology Co., Ltd.