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ChemicalBook >> CAS DataBase List >> α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile price.
  • $36 - $2839
  • Product name: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
  • CAS: 218136-59-5
  • MF: C27H29N5
  • MW: 423.55
  • EINECS:
  • MDL Number:MFCD11226148
  • Synonyms:SC 26196;α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;alpha,alpha-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;α,α-Diphenyl-4-[(3-pyridinylMethylene)aMino]-1-piperazine;2,2-diphenyl-5-{4-[(E)-(pyridin-3-ylMethylidene)aMino]piperazin-1-yl}pentanenitrile;PF-o6341724;(E)-2,2-diphenyl-5-(4-((pyridin-3-ylMethylene)aMino)piperazin-1-yl)pentanenitrile;2,2-diphenyl-5-(4-[[(1 E)-pyridin-3-yl-methylidene]amino]piperazin-1-yl)pentanenitrile
Price44 Properties Safety Information Description
44 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
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  • 50mg
  • 100.00mg
  • 50
  • 100MG
  • 250.00mg
  • 250mg
  • 10mM*1mLinDMSO
  • 1000mg
  • 1.00g
  • 1g
  • Manufactureraablocks
  • Product numberAA00C2O4
  • Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C2O4
  • Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
  • Packaging5mg
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C2O4
  • Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
  • Packaging10mg
  • Price$71
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C2O4
  • Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
  • Packaging25mg
  • Price$155
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C2O4
  • Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
  • Packaging50mg
  • Price$203
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203397
  • Product descriptionSC-26196 98.00%
  • Packaging25MG
  • Price$130
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203397
  • Product descriptionSC-26196 98.00%
  • Packaging100MG
  • Price$365
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging5MG
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7608
  • Product descriptionSC 26196
  • Packaging10mg
  • Price$165
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7608
  • Product descriptionSC 26196
  • Packaging50mg
  • Price$471
  • Updated2026-05-06
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2112
  • Product descriptionSC 26196
  • Packaging25mg
  • Price$313.5
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2112
  • Product descriptionSC 26196
  • Packaging5mg
  • Price$93.5
  • Updated2026-05-19
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180842
  • Product descriptionSC-26196 >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180842
  • Product descriptionSC-26196 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C2O4 2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98% 1mg $36 2026-05-28 Buy
aablocks AA00C2O4 2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98% 5mg $40 2026-05-28 Buy
aablocks AA00C2O4 2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98% 10mg $71 2026-05-28 Buy
aablocks AA00C2O4 2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98% 25mg $155 2026-05-28 Buy
aablocks AA00C2O4 2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98% 50mg $203 2026-05-28 Buy
ACHEMBLOCK X203397 SC-26196 98.00% 25MG $130 2026-05-27 Buy
ACHEMBLOCK X203397 SC-26196 98.00% 100MG $365 2026-05-27 Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 10MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 5MG $242 2021-12-16 Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 100MG $1686.3 2021-12-16 Buy
ApexBio Technology B7608 SC 26196 10mg $165 2026-05-06 Buy
ApexBio Technology B7608 SC 26196 50mg $471 2026-05-06 Buy
Axon Medchem Axon2112 SC 26196 25mg $313.5 2026-05-19 Buy
Axon Medchem Axon2112 SC 26196 5mg $93.5 2026-05-19 Buy
Biorbyt Ltd orb180842 SC-26196 >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb180842 SC-26196 >98% 100mg $838.1 2021-12-16 Buy
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Properties

Boiling point :650.213±55.00 °C(Press: 760.00 Torr)(predicted)
Density :1.097±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
pka :7.361±0.10(predicted)
color :white to tan
InChI :1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2/b30-22+
InChIKey :QFYKXKMYVYOUNJ-JBASAIQMSA-N
SMILES :N#CC(CCCN1CCN(CC1)\N=C\c2cccnc2)(c3ccccc3)c4ccccc4

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SC 26196 is an inhibitor of Δ6 desaturase (IC50 = 0.2 μM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). It is selective for Δ6 desaturase, as IC50 values for Δ5 and Δ9 desaturases exceed 200 μM and it has no effect on the conversion of dihomo-γ-linolenic acid to AA. SC 26196 is orally active in vivo, decreasing edema in the carrageenan paw edema model in mice. It also blocks aging-related increases in AA in myocardial cardiolipin in mice, attenuating contractile dysfunction without impacting mitochondrial oxidative stress.

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. VDM Biochemicals Chemsky (shanghai) International Co.,Ltd Nanjing Norris-Pharm Technology Co., Ltd Shanghai Witofly Chemical Co.,Ltd Nanjing Dulai Biotechnology Co., Ltd. Guangzhou Isun Pharmaceutical Co., Ltd AdooQ BioScience, LLC Bide Pharmatech Ltd.