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ChemicalBook >> CAS DataBase List >> N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine

N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine

$18 - $4725
Product name: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
CAS: 315703-52-7
MF: C19H18N4OS
MW: 350.44
EINECS:
MDL Number:MFCD01044465
Synonyms:N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine;Hh Signaling Antagonist VII, JK184;JK 184;N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine;2-ThiazolaMine, N-(4-ethoxyphenyl)-4-(2-MethyliMidazo[1,2-a]pyridin-3-yl)-;Hh Signaling Antagonist VII, JK184 - CAS 315703-52-7 - Calbiochem;CS-2369;JK184 (JK-184

Price47 Properties Safety Information Description

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aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Axon Medchem
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Sigma-Aldrich
TCI Chemical
Tocris
TRC
Usbiological

Package

5
25
1mg
5mg
10mg
25mg
50mg
100MG
250mg
1.00g
1G

Manufactureraablocks
Product numberAA00CHKK
Product descriptionJK184 95
Packaging5mg
Price$44
Updated2026-05-28
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Manufactureraablocks
Product numberAA00CHKK
Product descriptionJK184 95
Packaging10mg
Price$57
Updated2026-05-28
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Manufactureraablocks
Product numberAA00CHKK
Product descriptionJK184 95%
Packaging1mg
Price$18
Updated2026-05-28
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Manufactureraablocks
Product numberAA00CHKK
Product descriptionJK184 95
Packaging25mg
Price$96
Updated2026-05-28
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Manufactureraablocks
Product numberAA00CHKK
Product descriptionJK184 95
Packaging50mg
Price$151
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberP51724
Product descriptionJK 184 98%
Packaging100MG
Price$315
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberP51724
Product descriptionJK 184 98%
Packaging1G
Price$1890
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number3425AB
Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
Packaging1g
Price$1246
Updated2021-12-16
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ManufacturerAK Scientific
Product number3425AB
Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
Packaging25mg
Price$263
Updated2021-12-16
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ManufacturerAK Scientific
Product number3425AB
Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
Packaging5mg
Price$113
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA8652
Product descriptionJK 184
Packaging10mg
Price$98
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA8652
Product descriptionJK 184
Packaging5mg
Price$63
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA8652
Product descriptionJK 184
Packaging50mg
Price$320
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA8652
Product descriptionJK 184
Packaging100mg
Price$557
Updated2026-05-06
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ManufacturerArctom
Product numberSLK-S6565
Product descriptionJK184 99.56%
Packaging5mg
Price$140
Updated2026-05-26
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ManufacturerArctom
Product numberSLK-S6565
Product descriptionJK184 99.56%
Packaging25mg
Price$352
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00CHKK	JK184 95	5mg	$44	2026-05-28	Buy
aablocks	AA00CHKK	JK184 95	10mg	$57	2026-05-28	Buy
aablocks	AA00CHKK	JK184 95%	1mg	$18	2026-05-28	Buy
aablocks	AA00CHKK	JK184 95	25mg	$96	2026-05-28	Buy
aablocks	AA00CHKK	JK184 95	50mg	$151	2026-05-28	Buy
ACHEMBLOCK	P51724	JK 184 98%	100MG	$315	2026-05-27	Buy
ACHEMBLOCK	P51724	JK 184 98%	1G	$1890	2026-05-27	Buy
AK Scientific	3425AB	N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine	1g	$1246	2021-12-16	Buy
AK Scientific	3425AB	N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine	25mg	$263	2021-12-16	Buy
AK Scientific	3425AB	N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine	5mg	$113	2021-12-16	Buy
ApexBio Technology	A8652	JK 184	10mg	$98	2026-05-06	Buy
ApexBio Technology	A8652	JK 184	5mg	$63	2026-05-06	Buy
ApexBio Technology	A8652	JK 184	50mg	$320	2026-05-06	Buy
ApexBio Technology	A8652	JK 184	100mg	$557	2026-05-06	Buy
Arctom	SLK-S6565	JK184 99.56%	5mg	$140	2026-05-26	Buy
Arctom	SLK-S6565	JK184 99.56%	25mg	$352	2026-05-26	Buy

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Properties

storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
color :off-white to light brown
InChI :1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H,3H2,1-2H3,(H,21,22)
InChIKey :ROYXIPOUVGDTAO-UHFFFAOYSA-N

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501
H318	Causes serious eye damage	Serious eye damage/eye irritation	Category 1	Danger		P280, P305+P351+P338, P310

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

JK 184 is an imidazopyridine derivative that inhibits downstream hedgehog signaling, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). It does so by inhibiting alcohol dehydrogenase 7 (IC50 = 210 nM) and depolymerizing microtubules, preventing their assembly, which is crucial for Gli function. JK 184 exhibits antiproliferative activity in a range of cancer cell lines (L3.6pl, Panc 05.04, BxPC3, D283 med, Daoy; GI50s = 3-21 nM) and in L3.6pl and BxPC3 pancreatic cancer xenograft models (0.2 mg/mouse/day).

More related product prices

4-Aminodiphenylamine FORMANILIDE N-Methylformamide 315703-52-7 PTC-209 (PTC209 4-[[4-(2,7-DiMethyliMidazo[1,2-a]pyridin-3-yl)-2-thiazolyl]aMino]benzoic Acid

Suppliers and manufacturers

3B Pharmachem (Wuhan) International Co.,Ltd. Hangzhou Sage Chemical Co., Ltd. Chengdu NoVi Biotechnology Co., Ltd. SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD AdooQ BioScience, LLC CEG Chemical Science&Technology Co., Ltd. Bide Pharmatech Ltd. AdooQ Bioscience CHINA LETOPHARM LIMITED Shanghai Lollane Biological Technology Co.,Ltd.

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N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine

Properties

Safety Information

Description

Related product price

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