6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
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- $26 - $2691.1
- Product name: 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
- CAS: 371942-69-7
- MF: C25H21N7O3
- MW: 467.48
- EINECS:
- MDL Number:MFCD16038303
- Synonyms:6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide;YM 201636;YM201636/YM-201636;3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-;CS-335;6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide YM201636;YM 201636 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide;YM201636, >=98%
64 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 10mM(in1mLDMSO)
- 50.00mg
- 100.00mg
- 10mM*1mLinDMSO
- 250mg
- 1000mg
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1G
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging1mg
- Price$26
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging2mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging25mg
- Price$145
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging50mg
- Price$245
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYF0
- Product descriptionYM201636 98%
- Packaging100mg
- Price$416
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33812
- Product descriptionYM-201636 98%
- Packaging1G
- Price$1850
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33812
- Product descriptionYM-201636 98%
- Packaging100MG
- Price$355
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33812
- Product descriptionYM-201636 98%
- Packaging25MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33812
- Product descriptionYM-201636 98%
- Packaging5MG
- Price$50
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1094-M001
- Product descriptionYM201636 hydrochloride ≥95%
- Packaging1mg
- Price$108
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1094-M005
- Product descriptionYM201636 hydrochloride ≥95%
- Packaging5mg
- Price$173
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1094-M010
- Product descriptionYM201636 hydrochloride ≥95%
- Packaging10mg
- Price$270
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1094-M050
- Product descriptionYM201636 hydrochloride ≥95%
- Packaging50mg
- Price$918
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberY0272
- Product descriptionYM201636
- Packaging1mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000632
- Product descriptionYM 201636 95.00%
- Packaging5MG
- Price$811.86
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BYF0 | YM201636 98% | 1mg | $26 | 2026-05-28 | Buy |
| aablocks | AA00BYF0 | YM201636 98% | 2mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00BYF0 | YM201636 98% | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA00BYF0 | YM201636 98% | 25mg | $145 | 2026-05-28 | Buy |
| aablocks | AA00BYF0 | YM201636 98% | 50mg | $245 | 2026-05-28 | Buy |
| aablocks | AA00BYF0 | YM201636 98% | 100mg | $416 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33812 | YM-201636 98% | 1G | $1850 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33812 | YM-201636 98% | 100MG | $355 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33812 | YM-201636 98% | 25MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33812 | YM-201636 98% | 5MG | $50 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1094-M001 | YM201636 hydrochloride ≥95% | 1mg | $108 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1094-M005 | YM201636 hydrochloride ≥95% | 5mg | $173 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1094-M010 | YM201636 hydrochloride ≥95% | 10mg | $270 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1094-M050 | YM201636 hydrochloride ≥95% | 50mg | $918 | 2026-05-06 | Buy |
| AK Scientific | Y0272 | YM201636 | 1mg | $39 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000632 | YM 201636 95.00% | 5MG | $811.86 | 2021-12-16 | Buy |
Properties
Melting point :>226°C (dec.)
Density :1.446
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :Solid
color :Pale Beige to Light Beige
InChIKey :YBPIBGNBHHGLEB-UHFFFAOYSA-N
SMILES :N6(CCOCC6)c1nc(nc4c1[o]c5ncccc54)c2cc(ccc2)NC(=O)c3cnc(cc3)N
CAS DataBase Reference :371942-69-7
Density :1.446
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :Solid
color :Pale Beige to Light Beige
InChIKey :YBPIBGNBHHGLEB-UHFFFAOYSA-N
SMILES :N6(CCOCC6)c1nc(nc4c1[o]c5ncccc54)c2cc(ccc2)NC(=O)c3cnc(cc3)N
CAS DataBase Reference :371942-69-7
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA. YM-201636 also blocks retroviral exit by budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also inhibits basal and insulin-activated 2-deoxyglucose uptake (IC50 = 54 nM).Related product price
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