BETA-SECRETASE INHIBITOR IV
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- $121 - $2665
- Product name: BETA-SECRETASE INHIBITOR IV
- CAS: 797035-11-1
- MF: C31H38N4O5S
- MW: 578.72
- EINECS:
- MDL Number:MFCD09037559
- Synonyms:BETA-SECRETASE INHIBITOR IV;1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-;N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide;β-Secretase Inhibitor IV;3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide;N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE;BACE-1 inhibitor;γ-Secretase Inhibitor IV
24 prices
Selected condition：
Brand
- aablocks
- American Custom Chemicals Corporation
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 2x5mg
- 1 mg
- 500 μg
- 10mM*1mLinDMSO(Solution)
- 2mg
- 5mg
- 25mg
- 10MG
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA005IJH
- Product descriptionN1-[(1S,2R)-3-(Cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]-1,3-benzenedicarboxamide 97%
- Packaging2mg
- Price$192
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005IJH
- Product descriptionN1-[(1S,2R)-3-(Cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]-1,3-benzenedicarboxamide 97%
- Packaging5mg
- Price$260
- Updated2026-05-28
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004704
- Product description1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]- 95.00%
- Packaging2MG
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004704
- Product description1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]- 95.00%
- Packaging10MG
- Price$1270.5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging25mg
- Price$2337
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging10mg
- Price$1169
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$931
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging10mM*1mLinDMSO(Solution)
- Price$931
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging5mg
- Price$732
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10133
- Product descriptionβ-Secretase Inhibitor IV 99.19%
- Packaging1mg
- Price$228
- Updated2026-05-26
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1125
- Product descriptionBACE-1Inhibitor 97%
- Packaging2x5mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1125
- Product descriptionBACE-1 Inhibitor 97%
- Packaging2mg
- Price$121
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1125
- Product descriptionBACE-1 Inhibitor 97%
- Packaging5mg
- Price$176
- Updated2026-05-19
- Buy
- ManufacturerCayman Chemical
- Product number23388
- Product descriptionβ-Secretase Inhibitor IV ≥98%
- Packaging500μg
- Price$148
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number23388
- Product descriptionβ-Secretase Inhibitor IV ≥98%
- Packaging1mg
- Price$279
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number23388
- Product descriptionβ-Secretase Inhibitor IV ≥98%
- Packaging5mg
- Price$1093
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005IJH | N1-[(1S,2R)-3-(Cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]-1,3-benzenedicarboxamide 97% | 2mg | $192 | 2026-05-28 | Buy |
| aablocks | AA005IJH | N1-[(1S,2R)-3-(Cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]-1,3-benzenedicarboxamide 97% | 5mg | $260 | 2026-05-28 | Buy |
| American Custom Chemicals Corporation | API0004704 | 1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]- 95.00% | 2MG | $255 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004704 | 1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]- 95.00% | 10MG | $1270.5 | 2021-12-16 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 25mg | $2337 | 2026-05-26 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 10mg | $1169 | 2026-05-26 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 10mM*1mLinDMSO(Solid+Solvent) | $931 | 2026-05-26 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 10mM*1mLinDMSO(Solution) | $931 | 2026-05-26 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 5mg | $732 | 2026-05-26 | Buy |
| Arctom | HY-10133 | β-Secretase Inhibitor IV 99.19% | 1mg | $228 | 2026-05-26 | Buy |
| Axon Medchem | Axon1125 | BACE-1Inhibitor 97% | 2x5mg | $242 | 2021-12-16 | Buy |
| Axon Medchem | Axon1125 | BACE-1 Inhibitor 97% | 2mg | $121 | 2026-05-19 | Buy |
| Axon Medchem | Axon1125 | BACE-1 Inhibitor 97% | 5mg | $176 | 2026-05-19 | Buy |
| Cayman Chemical | 23388 | β-Secretase Inhibitor IV ≥98% | 500μg | $148 | 2026-04-30 | Buy |
| Cayman Chemical | 23388 | β-Secretase Inhibitor IV ≥98% | 1mg | $279 | 2026-04-30 | Buy |
| Cayman Chemical | 23388 | β-Secretase Inhibitor IV ≥98% | 5mg | $1093 | 2026-04-30 | Buy |
Properties
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :13.72±0.46(Predicted)
color :Off-white to light yellow
InChIKey :VPNIQGRFZCTBEZ-SPTGULJVSA-N
SMILES :O=C(C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNC3CC3)=O)=CC(N(S(C)(=O)=O)C)=C1)N[C@H](C)C4=CC=CC=C4
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :13.72±0.46(Predicted)
color :Off-white to light yellow
InChIKey :VPNIQGRFZCTBEZ-SPTGULJVSA-N
SMILES :O=C(C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNC3CC3)=O)=CC(N(S(C)(=O)=O)C)=C1)N[C@H](C)C4=CC=CC=C4
Safety Information
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Description
β-Secretase Inhibitor IV, a cell-permeable isophthalamide compound containing a hydroxyethylamine motif which binds to BACE-1 active site and potently blocks its proteolytic activity. The compound displays greater selectivity over other aspartyl proteases. β-Secretase Inhibitor IV is an inhibitor of BACE and BACE2.More related product prices
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