ChemicalBook >> CAS DataBase List >>BETA-SECRETASE INHIBITOR IV
BETA-SECRETASE INHIBITOR IV
- CAS No.
- 797035-11-1
- Chemical Name:
- BETA-SECRETASE INHIBITOR IV
- Synonyms
- BACE-1 inhibitor;β-Secretase Inhibitor IV;γ-Secretase Inhibitor IV;γ-Secretase Inhibitor IV;BETA-SECRETASE INHIBITOR IV;βSecretase Inhibitor IV,β Secretase Inhibitor IV;N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE;N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide;3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide;1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
- CBNumber:
- CB8835547
- Molecular Formula:
- C31H38N4O5S
- Molecular Weight:
- 578.72
- MDL Number:
- MFCD09037559
- MOL File:
- 797035-11-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-11 19:39:08
| Density | 1.30±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml |
| form | A crystalline solid |
| pka | 13.72±0.46(Predicted) |
| color | Off-white to light yellow |
| InChIKey | VPNIQGRFZCTBEZ-SPTGULJVSA-N |
| SMILES | O=C(C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNC3CC3)=O)=CC(N(S(C)(=O)=O)C)=C1)N[C@H](C)C4=CC=CC=C4 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
BETA-SECRETASE INHIBITOR IV price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 565794 | β-Secretase Inhibitor IV InSolution |
797035-11-1 | 500 μg | $190 | 2026-04-30 | Buy |
| Sigma-Aldrich | 565788 | β-Secretase Inhibitor IV β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC₅₀ = 15 nM for human BACE-1). | 797035-11-1 | 1 mg | $351 | 2026-04-30 | Buy |
| Sigma-Aldrich | 565761 | γ-Secretase Inhibitor IV The γ-Secretase Inhibitor IV controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications. | 1 mg | $189 | 2026-04-30 | Buy | |
| Cayman Chemical | 23388 | β-Secretase Inhibitor IV ≥98% | 797035-11-1 | 500μg | $148 | 2026-04-30 | Buy |
| Cayman Chemical | 23388 | β-Secretase Inhibitor IV ≥98% | 797035-11-1 | 1mg | $279 | 2026-04-30 | Buy |
BETA-SECRETASE INHIBITOR IV Chemical Properties, Uses, Production
Uses
beta-Secretase Inhibitor IV is a compound that binds to the active site of BACE-1 and potently blocks its proteolytic activity.
Biological Activity
Cell permeable: yes', 'Primary Target
β-Secretase', 'Reversible: yes', 'Target IC50: 15 nM for BACE-1, human and 29 nM for sAPP_NF in HEK293-APPNFEV cells
BETA-SECRETASE INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 46)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD | 13816107857 | sales@fortunechem-sh.com | China | 981 | 58 |
| Shanghai SunSyn Pharmaceutical Co., Ltd. | 021-18621020637 18621020637 | sales@sunsynpharma.com | China | 297 | 55 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Alabiotech Inc. | 001-619-354-5251 | sales@alabiotech-e.com | United States | 972 | 60 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
View Latest Price from BETA-SECRETASE INHIBITOR IV manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | β-Secretase Inhibitor IV
797035-11-1
|
$917.00-3590.00 | 10g | TargetMol Chemicals Inc. |
-
- β-Secretase Inhibitor IV
797035-11-1
- $917.00-3590.00
- TargetMol Chemicals Inc.
797035-11-1 (BETA-SECRETASE INHIBITOR IV) Related Search:
BETA-SECRETASE INHIBITOR IV
1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide
β-Secretase Inhibitor IV
3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE
BACE-1 inhibitor
γ-Secretase Inhibitor IV
βSecretase Inhibitor IV,β Secretase Inhibitor IV
γ-Secretase Inhibitor IV
797035-11-1
C31H38N4O5S
Human β-secretase (BACE-1) inhibitor.
