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ChemicalBook >> CAS DataBase List >> Capmatinib

Capmatinib

Capmatinib price.
  • $50 - $1208.7
  • Product name: Capmatinib
  • CAS: 1029712-80-8
  • MF: C23H17FN6O
  • MW: 412.42
  • EINECS:813-241-9
  • MDL Number:MFCD18633285
  • Synonyms:INCB028060;CapMatinib (INCB28060);CapMatinib;NC280 BenzaMide,2-fluoro-N-Methyl-4-[7-(6-quinolinylMethyl)iMidazo[1,2-b][1,2,4]triazin-2-yl]-;NVP-INC280;2-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamide Capmatinib (INCB28060);INCB28060, INC280;INC28060
28 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • 10g
  • ManufacturerAK Scientific
  • Product numberY0337
  • Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
  • Packaging10mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0337
  • Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
  • Packaging50mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0337
  • Product description2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
  • Packaging100mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013709
  • Product description2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YLMETHYL)IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE 95.00%
  • Packaging10MG
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8448
  • Product descriptionINCB28060
  • Packaging10mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8448
  • Product descriptionINCB28060
  • Packaging50mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8448
  • Product descriptionINCB28060
  • Packaging100mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60251
  • Product descriptionCapmatinib(INCB28060) ≥98%
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181031
  • Product descriptionCapmatinib(INCB28060) >98%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181031
  • Product descriptionCapmatinib(INCB28060) >98%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181031
  • Product descriptionCapmatinib(INCB28060) >98%
  • Packaging1000mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF40658
  • Product descriptionCapmatinib
  • Packaging250mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF40658
  • Product descriptionCapmatinib
  • Packaging500mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20056
  • Product descriptionINCB 28060 ≥98%
  • Packaging5mg
  • Price$88
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20056
  • Product descriptionINCB 28060 ≥98%
  • Packaging10mg
  • Price$157
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20056
  • Product descriptionINCB 28060 ≥98%
  • Packaging50mg
  • Price$647
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0337 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide 10mg $153 2021-12-16 Buy
AK Scientific Y0337 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide 50mg $205 2021-12-16 Buy
AK Scientific Y0337 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide 100mg $259 2021-12-16 Buy
American Custom Chemicals Corporation API0013709 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YLMETHYL)IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE 95.00% 10MG $315 2021-12-16 Buy
ApexBio Technology A8448 INCB28060 10mg $98 2021-12-16 Buy
ApexBio Technology A8448 INCB28060 50mg $315 2021-12-16 Buy
ApexBio Technology A8448 INCB28060 100mg $525 2021-12-16 Buy
Arctom CFN60251 Capmatinib(INCB28060) ≥98% 20mg $50 2021-12-16 Buy
Biorbyt Ltd orb181031 Capmatinib(INCB28060) >98% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb181031 Capmatinib(INCB28060) >98% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181031 Capmatinib(INCB28060) >98% 1000mg $1208.7 2021-12-16 Buy
Biosynth Carbosynth FF40658 Capmatinib 250mg $550 2021-12-16 Buy
Biosynth Carbosynth FF40658 Capmatinib 500mg $800 2021-12-16 Buy
Cayman Chemical 20056 INCB 28060 ≥98% 5mg $88 2024-03-01 Buy
Cayman Chemical 20056 INCB 28060 ≥98% 10mg $157 2024-03-01 Buy
Cayman Chemical 20056 INCB 28060 ≥98% 50mg $647 2024-03-01 Buy

Properties

Melting point :>250°C (dec.)
Density :1.40
vapor pressure :0-0Pa at 20-25℃
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.82±0.46(Predicted)
form :Solid
color :Pale Yellow to Light Yellow
InChI :InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
InChIKey :LIOLIMKSCNQPLV-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(C2=NN3C(CC4=CC=C5C(=C4)C=CC=N5)=CN=C3N=C2)C=C1F
LogP :1.6-2.2 at 35℃ and pH7-9

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Capmatinib is a competitive inhibitor with very potent and selective activity against MET compared to other kinases.

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