Leucettine L41
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- $65 - $2200
- Product name: Leucettine L41
- CAS: 1112978-84-3
- MF: C17H13N3O3
- MW: 307.3
- EINECS:
- MDL Number:
- Synonyms:Leucettine L41;4H-Imidazol-4-one, 5-(1,3-benzodioxol-5-ylmethylene)-3,5-dihydro-2-(phenylamino)-, (5Z)-;Leucettine L41,Leucettine L-41;(Z)-4-(Benzo[d][1,3]dioxol-5-ylmethylene)-2-(phenylamino)-1H-imidazol-5(4H)-one
21 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Usbiological
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25MG
- Manufactureraablocks
- Product numberAA0097CV
- Product descriptionLeucettine L41 99%
- Packaging10mg
- Price$107
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD279652
- Product descriptionLeucettine L41 98%
- Packaging5MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD279652
- Product descriptionLeucettine L41 98%
- Packaging25MG
- Price$705
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-MR-C0023-M025
- Product descriptionLeucettine L41 ≥98%(NMR)
- Packaging25mg
- Price$890
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-MR-C0023-M005
- Product descriptionLeucettine L41 ≥98%(NMR)
- Packaging5mg
- Price$230
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-MR-C0023-M001
- Product descriptionLeucettine L41 ≥98%(NMR)
- Packaging1mg
- Price$65
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-117049
- Product descriptionLeucettine L41 98.98%
- Packaging10mg
- Price$409
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-117049
- Product descriptionLeucettine L41 98.98%
- Packaging5mg
- Price$219
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberMUB97884
- Product descriptionLeucettine L41
- Packaging1mg
- Price$343.75
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberMUB97884
- Product descriptionLeucettine L41
- Packaging2mg
- Price$481.26
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberMUB97884
- Product descriptionLeucettine L41
- Packaging5mg
- Price$756.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberMUB97884
- Product descriptionLeucettine L41
- Packaging10mg
- Price$1168.8
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberMUB97884
- Product descriptionLeucettine L41
- Packaging25mg
- Price$2200
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number29225
- Product descriptionLeucettine L41 ≥98%
- Packaging10mg
- Price$493
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number29225
- Product descriptionLeucettine L41 ≥98%
- Packaging1mg
- Price$69
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number29225
- Product descriptionLeucettine L41 ≥98%
- Packaging5mg
- Price$263
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0097CV | Leucettine L41 99% | 10mg | $107 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD279652 | Leucettine L41 98% | 5MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD279652 | Leucettine L41 98% | 25MG | $705 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-MR-C0023-M025 | Leucettine L41 ≥98%(NMR) | 25mg | $890 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-MR-C0023-M005 | Leucettine L41 ≥98%(NMR) | 5mg | $230 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-MR-C0023-M001 | Leucettine L41 ≥98%(NMR) | 1mg | $65 | 2026-05-06 | Buy |
| Arctom | HY-117049 | Leucettine L41 98.98% | 10mg | $409 | 2026-05-26 | Buy |
| Arctom | HY-117049 | Leucettine L41 98.98% | 5mg | $219 | 2026-05-26 | Buy |
| Biosynth | MUB97884 | Leucettine L41 | 1mg | $343.75 | 2026-06-04 | Buy |
| Biosynth | MUB97884 | Leucettine L41 | 2mg | $481.26 | 2026-06-04 | Buy |
| Biosynth | MUB97884 | Leucettine L41 | 5mg | $756.25 | 2026-06-04 | Buy |
| Biosynth | MUB97884 | Leucettine L41 | 10mg | $1168.8 | 2026-06-04 | Buy |
| Biosynth | MUB97884 | Leucettine L41 | 25mg | $2200 | 2026-06-04 | Buy |
| Cayman Chemical | 29225 | Leucettine L41 ≥98% | 10mg | $493 | 2026-04-30 | Buy |
| Cayman Chemical | 29225 | Leucettine L41 ≥98% | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 29225 | Leucettine L41 ≥98% | 5mg | $263 | 2026-04-30 | Buy |
Properties
Melting point :>260 °C(Solvent: Ethanol)
Boiling point :475.009±55.00 °C(Press: 760.00 Torr)(predicted)
Density :1.419±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble; Ethanol: soluble
form :A solid
pka :-0.429±0.20(predicted)
color :Light yellow to yellow
Boiling point :475.009±55.00 °C(Press: 760.00 Torr)(predicted)
Density :1.419±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble; Ethanol: soluble
form :A solid
pka :-0.429±0.20(predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 μM, respectively).1 It also inhibits GSK3α/β and Pim1 with IC50 values of 0.41 and 4.1 μM, respectively. It inhibits phosphorylation of the serine/arginine (SR) protein 9G8 by DYRK2, DYRK3, CLK1, CLK2, and CLK4 and inhibits TNF-α-induced SRp75 and SRp55 phosphorylation in human microvascular endothelial cells when used at concentrations ranging from 0.1 to 10 μM. Leucettine L41 modulates alternative pre-RNA splicing of a synthetic CLK1 minigene in a reporter model. It prevents lipid peroxidation and the accumulation of reactive oxygen species (ROS) induced by amyloid-β 25-35 in the hippocampus in a mouse model of Alzheimer’s disease-like toxicity.2 Leucettine L41 (0.4, 1.2, and 4 μg, i.c.v.) also prevents memory deficits induced by amyloid-β 25-35 in the same model.Related product price
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Suppliers and manufacturers
BOC Sciences
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InvivoChem
HANGZHOU CLAP TECHNOLOGY CO.,LTD
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Suzhou Chenrui Biotechnology Co. LTD
