Pifithrin-α (PFTα)
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- $20 - $3108
- Product name: Pifithrin-α (PFTα)
- CAS: 63208-82-2
- MF: C16H19BrN2OS
- MW: 367.3
- EINECS:
- MDL Number:MFCD00417851
- Synonyms:1-(4-METHYLPHENYL)-2-(4,5,6,7-TETRAHYDRO-2-IMINO-3(2H)-BENZOTHIAZOLYL)ETHANONE, MONOHYDROBROMIDE;Pifithrin-Hydrobromide;2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide;PFT-α,Pifithrin-α;Zinc03874684;Ethanone, 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-iMino-3(2H)-benzothiazolyl)-, MonohydrobroMide;Pifithrin-alpha . HBr;2-(2-iMino-4,5,6,7-tetrahydrobenzo[d]thiazol-3(2H)-yl)-1-p-tolylethanone hydrobroMide
79 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Usbiological
Package
- 200mg
- 25.00g
- 10mM*1mLinDMSO(Solution)
- 2x50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 500mg
- 50.00g
- 100.00g
- 5g
- 10mM*1mLinDMSO
- 1mg
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 1G
- 100mg
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging1mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging10mg
- Price$39
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging25mg
- Price$74
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging50mg
- Price$117
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98%
- Packaging100mg
- Price$181
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TV
- Product description2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide ≥97%
- Packaging250mg
- Price$343
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70230
- Product description1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide 98%
- Packaging1G
- Price$760
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70230
- Product description1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide 98%
- Packaging100MG
- Price$240
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0004-M025
- Product descriptionPifithrin-α · hydrobromide ≥98%(HPLC+NMR)
- Packaging25mg
- Price$180
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0004-M010
- Product descriptionPifithrin-α · hydrobromide ≥98%(HPLC+NMR)
- Packaging10mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0004-M005
- Product descriptionPifithrin-α · hydrobromide ≥98%(HPLC+NMR)
- Packaging5mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberX5922
- Product descriptionPifithrin-alpha
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5922
- Product descriptionPifithrin-alpha
- Packaging50mg
- Price$409
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA201732
- Product description2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+%
- Packaging250mg
- Price$312
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA201732
- Product description2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+%
- Packaging100mg
- Price$189
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 1mg | $20 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 10mg | $39 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 25mg | $74 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 50mg | $117 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide 98% | 100mg | $181 | 2026-05-28 | Buy |
| aablocks | AA0036TV | 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide ≥97% | 250mg | $343 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q70230 | 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide 98% | 1G | $760 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70230 | 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide 98% | 100MG | $240 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-0004-M025 | Pifithrin-α · hydrobromide ≥98%(HPLC+NMR) | 25mg | $180 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-0004-M010 | Pifithrin-α · hydrobromide ≥98%(HPLC+NMR) | 10mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-0004-M005 | Pifithrin-α · hydrobromide ≥98%(HPLC+NMR) | 5mg | $50 | 2026-05-06 | Buy |
| AK Scientific | X5922 | Pifithrin-alpha | 10mg | $110 | 2021-12-16 | Buy |
| AK Scientific | X5922 | Pifithrin-alpha | 50mg | $409 | 2021-12-16 | Buy |
| Ambeed | A201732 | 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+% | 250mg | $312 | 2021-12-16 | Buy |
| Ambeed | A201732 | 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+% | 100mg | $189 | 2021-12-16 | Buy |
Properties
Melting point :192.1-192.5 °C(lit.)
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :9.11(at 25℃)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
InChIKey :HAGVCKULCLQGRF-UHFFFAOYSA-N
SMILES :C12CCCCC=1SC(=N)N2CC(=O)C1=CC=C(C)C=C1.Br
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :9.11(at 25℃)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
InChIKey :HAGVCKULCLQGRF-UHFFFAOYSA-N
SMILES :C12CCCCC=1SC(=N)N2CC(=O)C1=CC=C(C)C=C1.Br
Safety Information
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Description
Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. It prevents p53-mediated apoptosis induced by cytotoxic compounds in C8 cells at 10 μM and in human umbilical vein endothelial cells at 30 μM. Pifithrin-α can also protect cells from DNA damage-induced apoptosis by a p53-independent mechanism that might involve cyclin D1.More related product prices
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