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ChemicalBook >> CAS DataBase List >> TP-3654

TP-3654

$21 - $1900
Product name: TP-3654
CAS: 1361951-15-6
MF: C22H25F3N4O
MW: 418.46
EINECS:-0
MDL Number:MFCD28502206
Synonyms:TP-3654;CS-2702;TP3654 ;TP 3654;Cyclohexanemethanol, α,α-dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]-, trans-;TP3654,inhibit,Pim,TP 3654,Pim kinases,Inhibitor,TP-3654;2-(trans-4-((3-(3-(Trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol;TP-3654, 10 mM in DMSO;TP-3654 ，S6774

Price30 Properties Safety Information Description

30 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Arctom
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

Package

1mg
5mg
10mg
25mg
50mg
100mg
250MG
1G

Manufactureraablocks
Product numberAA01EOGQ
Product descriptiontrans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol ≥98%
Packaging5mg
Price$21
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EOGQ
Product descriptiontrans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol ≥98%
Packaging10mg
Price$37
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EOGQ
Product descriptiontrans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%
Packaging25mg
Price$63
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EOGQ
Product descriptiontrans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%
Packaging50mg
Price$102
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EOGQ
Product descriptiontrans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%
Packaging100mg
Price$147
Updated2026-05-30
Buy

ManufacturerACHEMBLOCK
Product numberX203344
Product descriptionTP-3654 98.00%
Packaging100MG
Price$245
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberX203344
Product descriptionTP-3654 98.00%
Packaging250MG
Price$410
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberX203344
Product descriptionTP-3654 98.00%
Packaging1G
Price$1230
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number9865DS
Product description2-[4-[[3-[3-(Trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol
Packaging25mg
Price$343
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number9865DS
Product description2-[4-[[3-[3-(Trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol
Packaging5mg
Price$160
Updated2021-12-16
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ManufacturerArctom
Product numberSLK-S6774
Product descriptionTP-3654 99.94%
Packaging5mg
Price$140
Updated2026-05-26
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ManufacturerArctom
Product numberSLK-S6774
Product descriptionTP-3654 99.94%
Packaging25mg
Price$283
Updated2026-05-26
Buy

ManufacturerCayman Chemical
Product number29571
Product descriptionTP-3654 ≥98%
Packaging25mg
Price$242
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number29571
Product descriptionTP-3654 ≥98%
Packaging5mg
Price$63
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number29571
Product descriptionTP-3654 ≥98%
Packaging10mg
Price$118
Updated2026-04-30
Buy

ManufacturerChemScene
Product numberCS-6293
Product descriptionTP-3654 99.96%
Packaging25mg
Price$195
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA01EOGQ	trans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol ≥98%	5mg	$21	2026-05-30	Buy
aablocks	AA01EOGQ	trans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol ≥98%	10mg	$37	2026-05-30	Buy
aablocks	AA01EOGQ	trans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%	25mg	$63	2026-05-30	Buy
aablocks	AA01EOGQ	trans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%	50mg	$102	2026-05-30	Buy
aablocks	AA01EOGQ	trans-α,α-Dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexanemethanol 99%	100mg	$147	2026-05-30	Buy
ACHEMBLOCK	X203344	TP-3654 98.00%	100MG	$245	2026-05-27	Buy
ACHEMBLOCK	X203344	TP-3654 98.00%	250MG	$410	2026-05-27	Buy
ACHEMBLOCK	X203344	TP-3654 98.00%	1G	$1230	2026-05-27	Buy
AK Scientific	9865DS	2-[4-[[3-[3-(Trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol	25mg	$343	2021-12-16	Buy
AK Scientific	9865DS	2-[4-[[3-[3-(Trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol	5mg	$160	2021-12-16	Buy
Arctom	SLK-S6774	TP-3654 99.94%	5mg	$140	2026-05-26	Buy
Arctom	SLK-S6774	TP-3654 99.94%	25mg	$283	2026-05-26	Buy
Cayman Chemical	29571	TP-3654 ≥98%	25mg	$242	2026-04-30	Buy
Cayman Chemical	29571	TP-3654 ≥98%	5mg	$63	2026-04-30	Buy
Cayman Chemical	29571	TP-3654 ≥98%	10mg	$118	2026-04-30	Buy
ChemScene	CS-6293	TP-3654 99.96%	25mg	$195	2026-06-04	Buy

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Properties

Density :1.340±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at -20°C
solubility :DMSO:86.0(Max Conc. mg/mL);200.74(Max Conc. mM)
Ethanol:6.0(Max Conc. mg/mL);14.34(Max Conc. mM) form :A crystalline solid
pka :15.184±0.29(predicted)
color :White to light yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TP-3654 is a second-generation PIM inhibitor, displaying submicromolar activity in pharmacodynamic biomarker modulation, cell proliferation studies, and colony formation assays.

Suppliers and manufacturers

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. Bide Pharmatech Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Chaolan Chemical Technology Center Beijing Solarbio Science & Tecnology Co., Ltd. Amadis Chemical Company Limited Shanghai CR Corporation Limited

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