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ChemicalBook >> CAS DataBase List >> TYRPHOSTIN AG 538

TYRPHOSTIN AG 538

TYRPHOSTIN AG 538 price.
  • $87 - $1170
  • Product name: TYRPHOSTIN AG 538
  • CAS: 133550-18-2
  • MF: C16H11NO5
  • MW: 297.26
  • EINECS:
  • MDL Number:MFCD03453581
  • Synonyms:AG 538 - CAS 133550-18-2 - Calbiochem;(αe)-α-[(3,4-dihydroxyphenyl)methylene]-3,4-dihydroxy-β-oxo-benzenepropanenitrile;AG 538, (αE)-α-[(3,4-Dihydroxyphenyl)methylene]-3,4-dihydroxy-β-oxo-benzenepropanenitrile;(E)-2-(3,4-dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile;Benzenepropanenitrile, α-[(3,4-dihydroxyphenyl)methylene]-3,4-dihydroxy-β-oxo-, (αE)-
15 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • Arctom
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • Manufactureraablocks
  • Product numberAA00A1CG
  • Product descriptionAG 538
  • Packaging1mg
  • Price$87
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A1CG
  • Product descriptionAG 538
  • Packaging5mg
  • Price$183
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A1CG
  • Product descriptionAG 538
  • Packaging10mg
  • Price$266
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A1CG
  • Product descriptionAG 538
  • Packaging25mg
  • Price$452
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A1CG
  • Product descriptionAG 538
  • Packaging50mg
  • Price$611
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY228890
  • Product descriptionTyrphostin AG 538 97.00%
  • Packaging25MG
  • Price$645
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY228890
  • Product descriptionTyrphostin AG 538 97.00%
  • Packaging10MG
  • Price$365
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY228890
  • Product descriptionTyrphostin AG 538 97.00%
  • Packaging100MG
  • Price$1170
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000031
  • Product descriptionTYRPHOSTIN AG 538 95.00%
  • Packaging25MG
  • Price$657.31
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-135436
  • Product descriptionAG 538 99.80%
  • Packaging50mg
  • Price$848
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135436
  • Product descriptionAG 538 99.80%
  • Packaging100mg
  • Price$1121
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135436
  • Product descriptionAG 538 99.80%
  • Packaging25mg
  • Price$621
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135436
  • Product descriptionAG 538 99.80%
  • Packaging10mg
  • Price$354
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135436
  • Product descriptionAG 538 99.80%
  • Packaging5mg
  • Price$235
  • Updated2026-05-26
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number658403
  • Product descriptionAG 538
  • Packaging5mg
  • Price$105
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00A1CG AG 538 1mg $87 2026-05-28 Buy
aablocks AA00A1CG AG 538 5mg $183 2026-05-28 Buy
aablocks AA00A1CG AG 538 10mg $266 2026-05-28 Buy
aablocks AA00A1CG AG 538 25mg $452 2026-05-28 Buy
aablocks AA00A1CG AG 538 50mg $611 2026-05-28 Buy
ACHEMBLOCK Y228890 Tyrphostin AG 538 97.00% 25MG $645 2026-05-27 Buy
ACHEMBLOCK Y228890 Tyrphostin AG 538 97.00% 10MG $365 2026-05-27 Buy
ACHEMBLOCK Y228890 Tyrphostin AG 538 97.00% 100MG $1170 2026-05-27 Buy
American Custom Chemicals Corporation KIN0000031 TYRPHOSTIN AG 538 95.00% 25MG $657.31 2021-12-16 Buy
Arctom HY-135436 AG 538 99.80% 50mg $848 2026-05-26 Buy
Arctom HY-135436 AG 538 99.80% 100mg $1121 2026-05-26 Buy
Arctom HY-135436 AG 538 99.80% 25mg $621 2026-05-26 Buy
Arctom HY-135436 AG 538 99.80% 10mg $354 2026-05-26 Buy
Arctom HY-135436 AG 538 99.80% 5mg $235 2026-05-26 Buy
Sigma-Aldrich 658403 AG 538 5mg $105 2026-04-30 Buy

Properties

Boiling point :637.5±55.0 °C(Predicted)
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 5mg/mL
form :solid
pka :7.48±0.35(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AG 538 is a potent, competitive inhibitor of IGF-IR (IGF-1 receptor kinase, IC50 = 400 nM). Reaction is competitive with respect to IGF-1R substrate. Also inhibits the phosphorylation of PTK substrate poly(Glu,Tyr) by IGF-1R, IR, EGF-R, and Src (IC50 = 60 nM, 113 nM, 370 nM, and 2.4 μM, respectively). Inhibits the phosphorylation of PKB at a much higher concentration (IC50 = 76 μM).