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ChemicalBook >> CAS DataBase List >> Trimethyl orthoacetate

Trimethyl orthoacetate

Trimethyl orthoacetate price.
  • $10 - $4153.78
  • Product name: Trimethyl orthoacetate
  • CAS: 1445-45-0
  • MF: C5H12O3
  • MW: 120.15
  • EINECS:215-892-9
  • MDL Number:MFCD00008477
  • Synonyms:1,1,1-trimethoxy-ethan ;Methyl orthoacetate;trimethyl-acetate ;Trimethylorthoaceate ;ORTHOACETIC ACID TRIMETHYL ESTER;TRIMETHYL ORTHOACETATE;1,1,1-Trimethoxyethane Orthoacetic Acid Trimethyl Ester;Methylorthoformic acid trimethyl ester
Price19 Properties Safety Information Description
19 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
Package
  • 100mg
  • 500mg
  • 2.500g
  • 5mL
  • 10ml
  • 25mL
  • 50ml
  • 100ml
  • 250ml
  • 500ML
  • 100 mL
  • 500 mL
  • ManufacturerAK Scientific
  • Product numberJ56541
  • Product descriptionTrimethyl Orthoacetate
  • Packaging5mL
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberS707
  • Product descriptionTrimethyl Orthoacetate
  • Packaging25mL
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0032534
  • Product descriptionTRIMETHYL ORTHOACETATE 95.00%
  • Packaging25ML
  • Price$1059.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0032534
  • Product descriptionTRIMETHYL ORTHOACETATE 95.00%
  • Packaging500ML
  • Price$4153.78
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number134351
  • Product description1,1,1-Trimethoxyethane 95%+
  • Packaging2.500g
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number134351
  • Product description1,1,1-Trimethoxyethane 95%+
  • Packaging500mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number134351
  • Product description1,1,1-Trimethoxyethane 95%+
  • Packaging100mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number237876
  • Product descriptionTrimethyl orthoacetate 99%
  • Packaging100ml
  • Price$64.4
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.18804
  • Product descriptionTrimethyl orthoacetate for synthesis
  • Packaging100mL
  • Price$71
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.18804
  • Product descriptionTrimethyl orthoacetate for synthesis
  • Packaging500mL
  • Price$157
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number237876
  • Product descriptionTrimethyl orthoacetate 99%
  • Packaging500ml
  • Price$201
  • Updated2026-04-30
  • Buy
  • ManufacturerTCI Chemical
  • Product numberO0115
  • Product descriptionTrimethyl Orthoacetate >98.0%(GC)
  • Packaging500mL
  • Price$129
  • Updated2026-04-30
  • Buy
  • ManufacturerTCI Chemical
  • Product numberO0115
  • Product descriptionTrimethyl Orthoacetate >98.0%(GC)
  • Packaging25mL
  • Price$30
  • Updated2026-04-30
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberL13369
  • Product descriptionTrimethyl orthoacetate, 98%
  • Packaging50ml
  • Price$44.65
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product number21818
  • Product descriptionTrimethyl orthoacetate, 98+% 98+%
  • Packaging100 mL
  • Price$51.65
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberL13369
  • Product descriptionTrimethyl orthoacetate, 98%
  • Packaging250ml
  • Price$99.65
  • Updated2026-04-24
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J56541 Trimethyl Orthoacetate 5mL $10 2021-12-16 Buy
AK Scientific S707 Trimethyl Orthoacetate 25mL $27 2021-12-16 Buy
American Custom Chemicals Corporation CHM0032534 TRIMETHYL ORTHOACETATE 95.00% 25ML $1059.65 2021-12-16 Buy
American Custom Chemicals Corporation CHM0032534 TRIMETHYL ORTHOACETATE 95.00% 500ML $4153.78 2021-12-16 Buy
Matrix Scientific 134351 1,1,1-Trimethoxyethane 95%+ 2.500g $420 2021-12-16 Buy
Matrix Scientific 134351 1,1,1-Trimethoxyethane 95%+ 500mg $136 2021-12-16 Buy
Matrix Scientific 134351 1,1,1-Trimethoxyethane 95%+ 100mg $64 2021-12-16 Buy
Sigma-Aldrich 237876 Trimethyl orthoacetate 99% 100ml $64.4 2026-04-30 Buy
Sigma-Aldrich 8.18804 Trimethyl orthoacetate for synthesis 100mL $71 2026-04-30 Buy
Sigma-Aldrich 8.18804 Trimethyl orthoacetate for synthesis 500mL $157 2026-04-30 Buy
Sigma-Aldrich 237876 Trimethyl orthoacetate 99% 500ml $201 2026-04-30 Buy
TCI Chemical O0115 Trimethyl Orthoacetate >98.0%(GC) 500mL $129 2026-04-30 Buy
TCI Chemical O0115 Trimethyl Orthoacetate >98.0%(GC) 25mL $30 2026-04-30 Buy
Thermo Scientific Chemicals L13369 Trimethyl orthoacetate, 98% 50ml $44.65 2026-04-24 Buy
Thermo Scientific Chemicals 21818 Trimethyl orthoacetate, 98+% 98+% 100 mL $51.65 2026-04-24 Buy
Thermo Scientific Chemicals L13369 Trimethyl orthoacetate, 98% 250ml $99.65 2026-04-24 Buy
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Properties

Boiling point :107-109 °C(lit.)
Density :0.944 g/mL at 25 °C(lit.)
vapor pressure :20 hPa (20 °C)
refractive index :n20/D 1.388(lit.)
Flash point :62 °F
storage temp. :Store below +30°C.
solubility :Chloroform (Sparingly), Methanol (Slightly)
form :Liquid
color :Clear colorless to slightly brown
Specific Gravity :0.960 (20/4℃)
Water Solubility :HYDROLYSIS
Sensitive :Moisture Sensitive
BRN :1098338
Henry's Law Constant :6.4×10-1 mol/(m3Pa) at 25℃, Guthrie (1973)
InChI :1S/C5H12O3/c1-5(6-2,7-3)8-4/h1-4H3
InChIKey :HDPNBNXLBDFELL-UHFFFAOYSA-N
SMILES :COC(C)(OC)OC
LogP :1.13 at 25℃
CAS DataBase Reference :1445-45-0(CAS DataBase Reference)
NIST Chemistry Reference :Ethane, 1,1,1-trimethoxy-(1445-45-0)
EPA Substance Registry System :Trimethyl orthoacetate (1445-45-0)

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Trimethyl orthoacetate is used as a diols can be protected as their 1-methoxyethylidene cyclic acetals (2-methoxy-2-methyl-1,3-dioxolanes) by acid-catalyzed exchange. It is mainly used as the chemical intermediates of the medicine. Some of the other applications includes it is mainly used as chemical intermediate of pharmaceutical and agricultural chemicals, used for compound medical intermediates of vitamin B1, vitamin A1 and sulfanilamide organism, used for dye and spices industry, Medicine, agricultural chemicals, paint additives.

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Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Trimethyl orthoacetate
$10.00 /1kg
Trimethyl orthoacetate CAS:1445-45-0
Hebei Yanxi Chemical Co., Ltd.
Trimethyl orthoacetate
$0.00 /1kg
Trimethyl orthoacetate CAS:1445-45-0
Hebei Chuanghai Biotechnology Co,.LTD
Trimethyl Orthoacetate
$5.70 /1KG
Trimethyl Orthoacetate CAS:1445-45-0
Chongqing Soarwin Technology Co., Ltd
Trimethyl Orthoacetate
$0.00 /1kg
Trimethyl Orthoacetate CAS:1445-45-0
Shanxi Naipu Import and Export Co.,Ltd
Trimethyl orthoacetate
$10.00 /1ASSAYS
Trimethyl orthoacetate CAS:1445-45-0
career henan chemical co
Trimethyl orthoacetate
$1.00 /1kg
Trimethyl orthoacetate CAS:1445-45-0
Capot Chemical Co.,Ltd.
Hangzhou Bayee Chemical Co., Ltd.
Henan Tianfu Chemical Co.,Ltd.
Jinan Finer Chemical Co., Ltd