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gland@glandpharma.com |
| Products Intro: |
Cas:1422144-42-0
ProductName:Netarsudil mesylate
Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
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| | Netarsudil Mesylate Basic information |
| Product Name: | Netarsudil Mesylate | | Synonyms: | AR-13324 (mesylate);Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester, methanesulfonate (1:2);AR-13324; AR13324; AR 13324; NETARSUDIL MESYLATE; RHOPRESSA;;Netarsudil Mesylate (AR-13324);(S)-4-(3-Amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate dimethanesulfonate;Netarsudil ophthalmi;AR-13324 Dimesylate;Netarsudil?API | | CAS: | 1422144-42-0 | | MF: | C28H27N3O3.2CH4O3S | | MW: | 645.75 | | EINECS: | | | Product Categories: | API | | Mol File: | 1422144-42-0.mol |  |
| | Netarsudil Mesylate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to yellow | | InChIKey | QQDRLKRHJOAQDC-FBHGDYMESA-N | | SMILES | S(O)(=O)(=O)C.N(C1C=CC2C=NC=CC=2C=1)C(=O)[C@@H](C1C=CC(=CC=1)COC(C1C=CC(=CC=1C)C)=O)CN.S(O)(=O)(=O)C |
| | Netarsudil Mesylate Usage And Synthesis |
| Uses | Netarsudil Mesylate is a Rho kinase inhibitor with norepinephrine transport inhibitory activity. It is FDA-approved for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or hypertensive eye disease. | | Side effects | Netarsudil ophthalmic solution: Conjunctival hyperemia, corneal verticillata, instillation site pain, conjunctival hemorrhage, instillation site erythema, corneal staining, blurred vision, increased lacrimation, eyelid erythema, reduced visual acuity.
Netarsudil and latanoprost ophthalmic solution: Conjunctival hyperemia, instillation site pain, corneal verticillata, conjunctival hemorrhage, ocular itching, decreased visual acuity, increased lacrimation, instillation site discomfort, blurred vision. |
| | Netarsudil Mesylate Preparation Products And Raw materials |
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