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Exendin-3 (9-39) amide

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Exendin-3 (9-39) amide manufacturers

  • Exendin (9-39)
  • Exendin (9-39) pictures
  • $1.00
  • 2018-07-30
  • CAS:133514-43-9
  • Min. Order: 5MG
  • Purity: >95%
  • Supply Ability: 5mg,10mg,25mg,100mg,1g,10g
Exendin-3 (9-39) amide Basic information
Product Name:Exendin-3 (9-39) amide
Synonyms:ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;EXENDIN 3 (9-39);EXENDIN-3 (9-39) AMIDE;EXENDIN (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;EXENDIN FRAGMENT 9-39;DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
CAS:133514-43-9
MF:C149H234N40O47S
MW:3369.76
EINECS:
Product Categories:Peptide;GLP-1 Receptor LigandsObesity Research;Cytokines Growth Factors and Hormones (Obesity);ExendinPeptides for Cell Biology;Hormones;Obesity Peptides;Obesity Research;Other Obesity Research Products;Glucagon receptor and related
Mol File:133514-43-9.mol
Exendin-3 (9-39) amide Structure
Exendin-3 (9-39) amide Chemical Properties
density 1.51
RTECS LF2460000
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
form Solid
color Off-white to pale purple
Water Solubility Soluble in water at 1mg/ml
SequenceAsp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
InChIKeyWSEVKKHALHSUMB-UHFFFAOYSA-N
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
Exendin-3 (9-39) amide Usage And Synthesis
DescriptionExendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.
UsesBiological probe.
UsesExendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.
General DescriptionExendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.
Biochem/physiol ActionsGLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4.
storageStore at -20°C
Exendin-3 (9-39) amide Preparation Products And Raw materials
Tag:Exendin-3 (9-39) amide(133514-43-9) Related Product Information
Exendin-4 (3-39) Alendronate sodium trihydrate OMEGA-CONOTOXIN MVIIC SDV-Exendin-3/4 Rosiptor Topiramate EXENDIN-3 EXENDIN 4, FAM-LABELED Exenatide acetate Exendin-3 (9-39) amide