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| | Acetiromate Basic information |
| Product Name: | Acetiromate | | Synonyms: | Acetiromate;3,5-Diiodo-4-(4-acetoxy-3-iodophenoxy)benzoic acid;4-(4-Acetoxy-3-iodophenoxy)-3,5-diiodobenzoic acid;Acetyltriiodothyroformic acid;Adecol;4-(4-acetyloxy-3-iodo-phenoxy)-3,5-diiodo-benzoic acid;4-(4-acetyloxy-3-iodophenoxy)-3,5-diiodobenzoic acid | | CAS: | 2260-08-4 | | MF: | C15H9I3O5 | | MW: | 649.931 | | EINECS: | | | Product Categories: | | | Mol File: | 2260-08-4.mol |  |
| | Acetiromate Chemical Properties |
| Melting point | 238°C | | density | 2.3074 (estimate) |
| | Acetiromate Usage And Synthesis |
| Originator | Acetiromate ,ZYF Pharm Chemical | | Uses | Acetiromate is a thyroxine analogue. Acetiromate is an antilipidemic drug for hyperlipidemia[1]. | | Manufacturing Process | To 3 parts of 3,5-diiodo-4-(3-iodo-4-hydroxyphenoxy)benzoic acid 10 parts of
acetic acid anhydride was added and mixture was heated on oil bath for some
hours. In the result of this reaction amorphous precipitate was obtained. After
recrystallization from glacial acetic acid 2.4 parts of 3,5-diiodo-4-(3-iodo-4-
acetoxyphenoxy)benzoic acid were obtained. | | Therapeutic Function | Antihyperlipidemic | | References | [1] S Kumaoka. Long-term administration of 3,5-diodo-4(3'-iodo4'-acetoxyphenoxy) benzoic acid (acetiromate) in hyperlipidemic patients. Endocrinol Jpn. 1974 Aug;21(4):355-60. DOI:10.1507/endocrj1954.21.355 |
| | Acetiromate Preparation Products And Raw materials |
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