L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

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L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Suppliers list
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L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Basic information
Product Name:L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
Synonyms:L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;JYS003;tert-Butyl (4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutyl)carbamate;VH032-C2-NH-Boc
CAS:2361119-87-9
MF:C31H45N5O6S
MW:615.78
EINECS:
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Mol File:2361119-87-9.mol
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Structure
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Chemical Properties
Boiling point 874.8±65.0 °C(Predicted)
density 1.216±0.06 g/cm3(Predicted)
pka12.68±0.46(Predicted)
Safety Information
MSDS Information
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Usage And Synthesis
UsesVH032-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C2-NH-Boc will remove the protecting group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032-C2-NH-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Preparation Products And Raw materials
Tag:L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-(2361119-87-9) Related Product Information
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