1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)-

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1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)- Basic information
Product Name:1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)-
Synonyms:1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)-;S 1924;2-[[(5-Methyl-2-pyridinyl)methyl]sulfinyl]-1H-thieno[3,4-d]imidazole
CAS:111371-30-3
MF:C12H11N3OS2
MW:277.37
EINECS:
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Mol File:111371-30-3.mol
1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)- Structure
1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)- Chemical Properties
Safety Information
MSDS Information
1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)- Usage And Synthesis
DescriptionS 1924 is a member of a new class of H+, K+-ATPase inhibitors.
UsesS 1924 is a potent H+, K+-ATPase inhibitor, with IC50 values of 10.3 and 1.6 μM at pH 7.4 and pH 6.0, respectively[1].
in vivo

S 1924 (0.5 mg/kg, iv) inhibits desglugastrin (100 μg/kg/h, iv)-stimulated gastric acid secretion in stomach-lumen-perfused rats[1].

References[1] Herling AW, et al. A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPase inhibitors. Pharmacology. 1988;36(5):289-97. DOI:10.1159/000138397
1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)- Preparation Products And Raw materials
Tag:1H-Thieno(3,4-d)imidazole, 2-(((5-methyl-2-pyridinyl)methyl)sulfinyl)-(111371-30-3) Related Product Information
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