| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Acitemate
CAS:64405-40-9
Purity:99.00% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Acitemate
CAS:64405-40-9
Purity:99.20% Package:1mg/RMB 2390;5mg/RMB 5270;10mg/RMB 7900
|
chinoin 123 manufacturers
- Acitemate
-
- $340.00 / 1mg
-
2026-01-05
- CAS:64405-40-9
- Min. Order:
- Purity: 99.23%
- Supply Ability: 10g
|
| | chinoin 123 Basic information |
| Product Name: | chinoin 123 | | Synonyms: | chinoin 123;4H-Pyrido[1,2-a]pyrimidine-9-acetic acid, 3-(ethoxycarbonyl)-6,7,8,9-tetrahydro-6-methyl-4-oxo-;2-(3-(Ethoxycarbonyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl)acetic acid | | CAS: | 64405-40-9 | | MF: | C14H18N2O5 | | MW: | 294.3 | | EINECS: | | | Product Categories: | | | Mol File: | 64405-40-9.mol |  |
| | chinoin 123 Chemical Properties |
| Melting point | 154-155 °C(Solv: ethanol (64-17-5)) | | Boiling point | 472.0±55.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | pka | 4.45±0.10(Predicted) |
| | chinoin 123 Usage And Synthesis |
| Originator | Acitemate ,Onbio Inc. | | Manufacturing Process | 23.6 g of 3-ethoxycarbonyl-7-methyl-4-oxo-6,7,8,9-tetrahydro-4Hpyrido[
1,2a]pyrimidine and 10.0 g of glyoxylic acid monohydrate are reacted
and the obtained 3-ethoxycarbonyl-7-methyl-9-carboxy(hydroxymethyl)-4-
oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine is heated in 150 ml ethanol
under stirring for 3 h. After cooling the crystals are filtered off and
recrystallized from ethanol. Thus 3-ethoxycarbonyl-7-methyl-9-
(carboxymethylene)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine
melting point 110°-112°C, is obtained (yield: 51%).
55.6 g of 3-ethoxycarbonyl-9-(carboxymethylene)-4-oxo-6,7,8,9-tetrahydro-
4H-pyrido[1,2a]pyrimidine are hydrogenated in 500 ml of ethanol in the
presence of 20.0 g of 9% by weight Pd/C catalyst containing metal. When 1
mole of hydrogen has been used up, the catalyst is removed from the reaction
mixture by filtration and the solution is evaporated under reduced pressure.
The 3-ethoxycarbonyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9-
acetic acid is obtained (yield: 57%), melting point 156°-157°C (recrystallized
from ethanol). | | Therapeutic Function | Platelet aggregation inhibitor, Antihyperlipidemic |
| | chinoin 123 Preparation Products And Raw materials |
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