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| | AD-5584 Basic information |
| Product Name: | AD-5584 | | Synonyms: | AD-5584;1-Piperidineacetamide, N-[(6-chloro-1H-benzimidazol-2-yl)methyl]-α-(4-fluorophenyl)-N-methyl- | | CAS: | 2306525-79-9 | | MF: | C22H24ClFN4O | | MW: | 414.9 | | EINECS: | | | Product Categories: | | | Mol File: | 2306525-79-9.mol |  |
| | AD-5584 Chemical Properties |
| Boiling point | 606.824±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.326±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 10.095±0.10(predicted) | | form | Solid | | color | White to off-white |
| | AD-5584 Usage And Synthesis |
| Uses | AD-5584 is an ACSS2 inhibitor with blood-brain permeability. AD-5584 can significantly reduce lipid storage, reduce colony formation, and increase cell death. AD-5584 has antitumor activity[1]. | | References | [1] Esquea E, et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073. DOI:10.1101/2023.12.22.573073 |
| | AD-5584 Preparation Products And Raw materials |
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