STING Agonist 12L

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STING Agonist 12L Suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
STING Agonist 12L Basic information
Product Name:STING Agonist 12L
Synonyms:STING Agonist 12L;Benzoic acid, 2-[([3,4′-bipyridazin]-6-ylcarbonyl)amino]-4-ethynyl-5-fluoro-
CAS:2913152-30-2
MF:C18H10FN5O3
MW:363.3
EINECS:
Product Categories:
Mol File:2913152-30-2.mol
STING Agonist 12L Structure
STING Agonist 12L Chemical Properties
Boiling point 604.710±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.554±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 5 mg/mlPBS (pH 7.2): 2 mg/ml
pka2.597±0.36(predicted)
Safety Information
MSDS Information
STING Agonist 12L Usage And Synthesis
UsesSTING agonist-34 (Compound 12L) is a potent STING agonist with an IC50 value of 1.15 μM and an EC50 of 0.38 μM in THP1 cells. STING agonist-34 could be used in cancer research[1].
References[1] Li R, et al. Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein. J Chem Inf Model. 2023 Oct 13. DOI:10.1021/acs.jcim.3c00984
[2] BIN SHAN, MINGYUE ZHENG*   Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists[J]. Journal of Medicinal Chemistry, 2023, 66 5: 3327-3347. DOI: 10.1021/acs.jmedchem.2c01714
STING Agonist 12L Preparation Products And Raw materials
Tag:STING Agonist 12L(2913152-30-2) Related Product Information
STING Agonist 12L 1H-Benzimidazole-5-carboxamide, 1,1'-(1,4-butanediyl)bis[2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]- 9(10H)-Acridinone, 2-methoxy-5,6-dimethyl- STING Agonist D61 STING agonist-3 diABZI STING agonist-1 Tautomerism