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| | METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE Basic information |
| Product Name: | METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE | | Synonyms: | METHYL TRIBENZYLGALLATE;METHYL 3,4,5-TRIBENZYLOXYBENZOATE;METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE;3,4,5-TRIS(BENZYLOXY)BENZOIC ACID METHYL ESTER;3,4,5-TRIBENZYLOXYBENZOIC ACID METHYL ESTER;methyl 3,4,5-tris(phenylmethoxy)benzoate;3,4,5-Tris(phenylMethoxy)benzoic Acid Methyl Ester;Methyl Tri-O-benzylgallate | | CAS: | 70424-94-1 | | MF: | C29H26O5 | | MW: | 454.51 | | EINECS: | | | Product Categories: | Building Blocks for Dendrimers;Functional Materials;Aromatics;Intermediates | | Mol File: | 70424-94-1.mol |  |
| | METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE Chemical Properties |
| Melting point | 98 °C | | Boiling point | 584.5±40.0 °C(Predicted) | | density | 1.191±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Acetone, Chloroform, Dichloromethane | | form | Solid | | color | White | | CAS DataBase Reference | 70424-94-1 |
| | METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Intermediate in the production of Gallic Acid derivatives. | | Synthesis | Benzyl bromide (4.4 g, 25.7 mmol) was added dropwise to a stirred solution of methyl 3,4,5-trihydroxybenzoate (0.94 g, 5.15 mmol) and potassium carbonate (6.56 g, 25.7 mmol) in N,N-dimethylformamide (DMF, 20 mL). The reaction mixture was stirred under nitrogen (N2) protection in an oil bath at 60 °C for 15 hours. Upon completion of the reaction, the reaction was quenched by adding an appropriate amount of water to the mixture and extracted with chloroform (3 × 20 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford methyl 3,4,5-tris(benzyloxy)benzoate (1.93 g, 90% yield) as a white solid. | | References | [1] Patent: EP1870403, 2007, A1. Location in patent: Page/Page column 95
[2] Patent: US2004/110790, 2004, A1. Location in patent: Page 14
[3] Bioscience, Biotechnology and Biochemistry, 2003, vol. 67, # 12, p. 2584 - 2590
[4] Patent: US7288273, 2007, B1. Location in patent: Page/Page column 38
[5] Synthetic Communications, 2002, vol. 32, # 20, p. 3149 - 3158 |
| | METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE Preparation Products And Raw materials |
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