| Company Name: |
Energy Chemical |
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400-0056266 |
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sales8178@energy-chemical.com |
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| | methyl 1-methyl-1H-pyrazole-3-carboxylate Basic information |
| | methyl 1-methyl-1H-pyrazole-3-carboxylate Chemical Properties |
| Boiling point | 108-110 °C(Press: 1 Torr) | | density | 1.18±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | -0.17±0.10(Predicted) | | Appearance | White to light yellow Solid | | InChI | InChI=1S/C6H8N2O2/c1-8-4-3-5(7-8)6(9)10-2/h3-4H,1-2H3 | | InChIKey | WUUOFOYBXXQAGD-UHFFFAOYSA-N | | SMILES | N1(C)C=CC(C(OC)=O)=N1 | | CAS DataBase Reference | 17827-61-1 |
| | methyl 1-methyl-1H-pyrazole-3-carboxylate Usage And Synthesis |
| Uses | Used as an intermediate in organic synthesis. | | Synthesis | A mixture of 2.11 g of pyrazole-3-carboxylic acid (V), 50 ml of methanol, and 0.5 ml of POCl3 was refluxed for 12 h. After cooling the reaction mixture was concentrated. The resulting crystals were washed with 20% sodium carbonate solution, dried at 55°C (1 mm Hg), and recrystallized from benzene. Methyl 1-methylpyrazole-3-carboxylate (VIII) was obtained similarly from 6.12 g of 1-methyl-3-pyrazole carboxylic acid VI, 50 ml of methanol and 0.5 ml of POCl3 . Yield 10.2 g (72.8%). bp 125°C (1 mm Hg). IR spectrum, ν, cm -1: 1520 (ring), 1730 (C═O). 1H NMR spectrum, δ, ppm (J, Hz): 3.77 s (3H, NCH3), 3.85 s (3H, OCH3), 6.68 d (1H, 4-H, J2.2), 7.1 br. s (1H, 5H). Found, %: C 51.63; H 5.85; N 20.28. C6H8N2O2. Calculated, %: C 51.42; H 5.71; N 20.00.
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| | methyl 1-methyl-1H-pyrazole-3-carboxylate Preparation Products And Raw materials |
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