- 2-Chlorocinnamic acid
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- $9.80 / 1KG
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2026-01-05
- CAS:3752-25-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 2-Chlorocinnamic acid
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- $32.00 / 1kg
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2025-09-25
- CAS:3752-25-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2-Chlorocinnamic acid
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- $0.00 / 1Kg
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2025-08-20
- CAS:3752-25-8
- Min. Order: 1Kg
- Purity: 99.99%
- Supply Ability: 20 tons
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| | 2-Chlorocinnamic acid Basic information |
| | 2-Chlorocinnamic acid Chemical Properties |
| Melting point | 208-210 °C(lit.) | | Boiling point | 260.71°C (rough estimate) | | density | 1.2377 (rough estimate) | | refractive index | 1.5426 (estimate) | | storage temp. | Room temperature. | | Water Solubility | Insoluble in water | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 4.23(at 25℃) | | form | powder to crystal | | color | White to Almost white | | BRN | 1365198 | | InChI | InChI=1S/C9H7ClO2/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6H,(H,11,12) | | InChIKey | KJRRTHHNKJBVBO-AATRIKPKSA-N | | SMILES | C(O)(=O)C=CC1=CC=CC=C1Cl | | CAS DataBase Reference | 3752-25-8(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Chlorocinnamic acid(3752-25-8) |
| | 2-Chlorocinnamic acid Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder. Insoluble in water, soluble in ethanol, ethyl acetate and other organic solvents. | | Uses | 2-Chlorocinnamic acid is a kind of trans-cinnamate. It is used in organic synthesis. | | Biological Functions | 2-Chlorocinnamic acid is a cinnamic acid derivative that inhibits the hydroxylation of phenylpropanoids. It has been shown to inhibit the activity of cinnamic acid derivatives and their hydroxylation in cell lines, which is linked to the inhibition of cellulose acetate synthesis. 2-Chlorocinnamic acid also has an inhibitory effect on the chloride ion and water molecule. The chloride ion may be needed for the formation of hydrochloric acid, which is necessary for cellulose acetate hydrolysis, while water molecules are involved in many biochemical reactions. 2-Chlorocinnamic acid affects human cell lines at temperatures between 10°C and 37°C and at regiospecific sites. This oxidative dehalogenation reaction catalyzed by R. rubra was found to be regiospecific for 2-chlorocinnamic acid; the chloride ion was probably removed after the ring fission reaction. | | Synthesis | O-chlorocinnamic acid is prepared by reacting o-phthalaldehyde with malonic acid. | | References | [1] Patent: EP1676838, 2006, A1. Location in patent: Page/Page column 17
[2] Patent: WO2006/69799, 2006, A1. Location in patent: Page/Page column 29-30 |
| | 2-Chlorocinnamic acid Preparation Products And Raw materials |
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