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| | O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Basic information |
| | O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Chemical Properties |
| Melting point | 212-216 °C(lit.) | | alpha | +4.0~+8.0°(c=10,dilHCl)(D/20) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Usage And Synthesis |
| Uses | L-4-Oxalysine hydrochloride is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China which has shown antitumor activities. | | Biological Activity | L-4-Oxalysine hydrochloride is a natural substance isolated from the culture medium of Streptomyces in China and has anticancer activity. | | in vitro | L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor. | | in vivo | L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma. | | References | [1] Dai ZQ, et al. Effect of L-4-oxalysine on ultrastructures of liver cells in mice. Zhongguo Yao Li Xue Bao. 1991 Jul;12(4):336-40. PMID:1807083 [2] Wang XW, et al. Immunostimulatory action of L-4-oxalysine counteracts immunosuppression induced by alpha-fetoprotein. Eur J Pharmacol. 1998 Jun 12;351(1):105-11. DOI:10.1016/s0014-2999(98)00277-5 |
| | O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Preparation Products And Raw materials |
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