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| | HUMAN SRANKL Basic information |
| Product Name: | HUMAN SRANKL | | Synonyms: | TRANCE;TNFSF11 PRIMER PAIR;TNF-RELATED ACTIVATION-INDUCED CYTOKINES (TRANCE);TNF-RELATED ACTIVATION-INDUCED CYTOKINES (TRANCE), HUMAN;RANK LIGAND;RANK LIGAND PRIMER PAIR;RANK LIGAND/TRANCE HUMAN;RANKL RECEPTOR, HUMAN | | CAS: | 207621-35-0 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN SRANKL Structure]() |
| | HUMAN SRANKL Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white | | biological source | rat | | Major Application | cell analysis |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN SRANKL Usage And Synthesis |
| Uses | RANK ligand from mouse has been used to visualize differentiated osteoclasts and to stimulate osteoclast differentiation. | | General Description | Tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) or receptor activator of nuclear factor-κB ligand (RANKL) is a type II transmembrane signaling receptor. It has a molecular weight of about 35kDa. The protein possesses an amino-terminal intracellular tail and a carboxy-terminal extracellular region, which has a connecting stalk and a receptor-binding domain. | | Biochem/physiol Actions | Tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) or RANKL has an important role in osteoclast function and differentiation. It binds to RANK and osteoprotegrin (OPG). Bioactivities of RANKL may be attributed to its binding to these two receptor molecules. Mouse and human RANKL share 85% amino acid sequence identity. |
| | HUMAN SRANKL Preparation Products And Raw materials |
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