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| | Propargyl-PEG3-Ms Basic information |
| Product Name: | Propargyl-PEG3-Ms | | Synonyms: | Propargyl-PEG3-Ms;Propargyl-PEG2-Ms;Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate;2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate - [P88013] | | CAS: | 943726-01-0 | | MF: | C8H14O5S | | MW: | 222.26 | | EINECS: | | | Product Categories: | | | Mol File: | 943726-01-0.mol |  |
| | Propargyl-PEG3-Ms Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Propargyl-PEG3-Ms Usage And Synthesis |
| Description | Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. | | Uses | Propargyl-PEG2-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] Bai S, et al. Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. J Med Chem. 2014 May 22;57(10):4239-51. DOI:10.1021/jm5001453 |
| | Propargyl-PEG3-Ms Preparation Products And Raw materials |
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