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Propargyl-PEG3-NH2 manufacturers
- Propargyl-PEG3-NH2
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2026-07-24
- CAS:932741-19-0
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG3-NH2 Basic information |
| Product Name: | Propargyl-PEG3-NH2 | | Synonyms: | Ethanamine, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-;Alkyne-PEG3-amine;2‐(2‐(2‐(prop‐2‐yn‐1‐yloxy)ethoxy)ethoxy)ethanamine;Propargyl-PEG3-NH2/Ethanamine, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-;NH2-PEG3-Al;2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanamine;3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)prop-1-yne;H2N-PEG3-Propargyl | | CAS: | 932741-19-0 | | MF: | C9H17NO3 | | MW: | 187.24 | | EINECS: | | | Product Categories: | peg | | Mol File: | 932741-19-0.mol |  |
| | Propargyl-PEG3-NH2 Chemical Properties |
| Boiling point | 267.4±25.0 °C(Predicted) | | density | 1.019±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 8.74±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow | | Appearance | colorlessoryellowish liquid | | InChI | InChI=1S/C9H17NO3/c1-2-4-11-6-8-13-9-7-12-5-3-10/h1H,3-10H2 | | InChIKey | MREICTHRFCQNJR-UHFFFAOYSA-N | | SMILES | C(N)COCCOCCOCC#C |
| | Propargyl-PEG3-NH2 Usage And Synthesis |
| Description | Propargyl-PEG3-amine is a PEG linker that is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group reacts with azides in copper catalyzed azide-alkyne Click Chemistry. | | Uses | Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG3-NH2 Preparation Products And Raw materials |
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