- Propargyl-PEG3-Br
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2026-07-24
- CAS:203740-63-0
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG3-Bromide Basic information |
| Product Name: | Propargyl-PEG3-Bromide | | Synonyms: | Propargyl-PEG3-Bromide;Alkyne-PEG3-Br;PROPARGYL-PEG3-BR;1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-;Propargyl-PEG3-Br/1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-;3- (2- (2- (2-bromoethoxy) ethoxy) ethoxy) propa-1-yne;Alkeyn-PEG3-Br;1-bromo-2-{2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy}ethane | | CAS: | 203740-63-0 | | MF: | C9H15BrO3 | | MW: | 251.12 | | EINECS: | | | Product Categories: | peg | | Mol File: | 203740-63-0.mol |  |
| | Propargyl-PEG3-Bromide Chemical Properties |
| Boiling point | 287.8±25.0 °C(Predicted) | | density | 1.300±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, stored under nitrogen, away from moisture | | solubility | Soluble in DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow |
| | Propargyl-PEG3-Bromide Usage And Synthesis |
| Description | Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst. | | Uses | Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG3-Bromide Preparation Products And Raw materials |
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