| Company Name: |
LGM Pharma |
| Tel: |
1-(800)-881-8210 |
| Email: |
inquiries@lgmpharma.com |
- Mometasone
-
- $15.00
-
2021-08-12
- CAS:105102-22-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- icariins
-
- $15.00
-
2021-07-13
- CAS:105102-22-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- icariins
-
- $15.00
-
2021-07-10
- CAS:105102-22-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
|
| | Mometasone Basic information |
| Product Name: | Mometasone | | Synonyms: | Mometasone (Mometasone Furoate EP Impurity G);MOMETASONE;9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;MometasoneFuroateBase;Mometasone Furoate EP Impurity G/Mometasone;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI);MOMETOSONE FUROATE | | CAS: | 105102-22-5 | | MF: | C22H28Cl2O4 | | MW: | 427.36 | | EINECS: | 818-819-4 | | Product Categories: | | | Mol File: | 105102-22-5.mol |  |
| | Mometasone Chemical Properties |
| Melting point | >211oC (dec.) | | Boiling point | 586.6±50.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | pka | 12.08±0.70(Predicted) | | form | Solid | | color | White to Pale Beige | | InChIKey | WOFMFGQZHJDGCX-MCUOXHNDNA-N | | SMILES | [C@]1(OC(=O)C2OC=CC=2)([C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C(CCl)=O |&1:0,9,12,14,24,26,28,31,r| | | CAS DataBase Reference | 105102-22-5(CAS DataBase Reference) |
| | Mometasone Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. It can be applied to the skin, inhaled, or used in the nose. It is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis. Mometasone furoate, not mometasone, is used in medical products. | | Definition | ChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone. | | Side effects | The most common side effects are an unpleasant smell and a dry or sore nose or throat. | | in vivo | Mometasone (0.1-3 mg/kg; intranasally) inhibits the increased airway sensitivity to aerosolized methacholine at the highest dose tested of 3 mg/kg, and dose-dependently inhibits the allergen-induced increase in Penh in a mouse model of allergic lung inflammation[3]. |
| | Mometasone Preparation Products And Raw materials |
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