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Nextpeptide Inc |
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- Acid-PEG4-S-PEG4-acid
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-
2025-06-07
- CAS:2055041-21-7
- Min. Order: 500mg
- Purity: >95.00%
- Supply Ability: 500mg
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| | Acid-PEG4-S-PEG4-Acid Basic information |
| | Acid-PEG4-S-PEG4-Acid Chemical Properties |
| Boiling point | 658.3±55.0 °C(Predicted) | | density | 1.190±0.06 g/cm3(Predicted) | | pka | 3.97±0.10(Predicted) |
| | Acid-PEG4-S-PEG4-Acid Usage And Synthesis |
| Description | Acid-PEG4-S-PEG4-acid contains two terminal carboxylic acid groups. The carboxylic acid groups can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media. | | Uses | Acid-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Acid-PEG4-S-PEG4-Acid Preparation Products And Raw materials |
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