HS-PEG4-CH2CH2COOH

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HS-PEG4-CH2CH2COOH manufacturers

  • Thiol-PEG4-acid
  • Thiol-PEG4-acid pictures
  • 2025-06-07
  • CAS:749247-06-1
  • Min. Order: 1g
  • Purity: >98.00%
  • Supply Ability: 1g
  • HS-PEG4-CH2CH2COOH
  • HS-PEG4-CH2CH2COOH pictures
  • $1.00
  • 2020-01-10
  • CAS:749247-06-1
  • Min. Order: 1g
  • Purity: 99.0%
  • Supply Ability: 100kg
HS-PEG4-CH2CH2COOH Basic information
Product Name:HS-PEG4-CH2CH2COOH
Synonyms:HS-PEG4-CH2CH2COOH;3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoic acid;Thiol-dPEG 4 acid;Propanoicacid, 3-[2-[2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy]ethoxy]-;HS-PEG4-CH2CH2COOH;Thiol-PEG4-acid;Thiol-PEG5-acid;Thiol-PEG4-propionic acid
CAS:749247-06-1
MF:C11H22O6S
MW:282.35
EINECS:
Product Categories:peg
Mol File:749247-06-1.mol
HS-PEG4-CH2CH2COOH Structure
HS-PEG4-CH2CH2COOH Chemical Properties
Boiling point 422.9±45.0 °C(Predicted)
density 1.156±0.06 g/cm3(Predicted)
storage temp. -20°C
pka4.28±0.10(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
HS Code 2930909899
MSDS Information
HS-PEG4-CH2CH2COOH Usage And Synthesis
DescriptionThiol-PEG4-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
UsesThiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitabilityreaction type: Pegylations
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
HS-PEG4-CH2CH2COOH Preparation Products And Raw materials
Tag:HS-PEG4-CH2CH2COOH(749247-06-1) Related Product Information
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