4-Pyridyl acetone

4-Pyridyl acetone Suppliers list

Company Name:	Shaoyuan Technology (Shanghai) Co., Ltd. Gold
Tel:	4000665055
Email:	marketing@accelachem.com

Company Name:	Nanjing Lanbai Chemical Co., Ltd. Gold
Tel:	025-85499326 15366059326;13813836665
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Company Name:	Nanjing Kaitian Chemical Co., Ltd Gold
Tel:	15951673915
Email:	377901895@qq.com

4-Pyridyl acetone manufacturers

4-Pyridyl acetone Basic information

Product Name:	4-Pyridyl acetone
Synonyms:	1-(4-Pyridyl)-2-propanone;4-Pyridinolacetone;(4-Pyridyl)acetone,98%;1-(4-Pyridinyl)-2-propanone CAS:;(4-PYRIDINEYL)-ACETONE;Einecs 228-605-7;1-pyridin-4-ylacetone;-Pyridyl acetone
CAS:	6304-16-1
MF:	C8H9NO
MW:	135.16
EINECS:	228-605-7
Product Categories:	Pyridines
Mol File:	6304-16-1.mol

4-Pyridyl acetone Chemical Properties

Melting point	13°C
Boiling point	143°C 20mm
density	1.046±0.06 g/cm3(Predicted)
refractive index	1.5225
Fp	143°C/20mm
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka	4.90±0.10(Predicted)
form	Oil
color	Light Brown to Brown
Water Solubility	Slightly soluble in water.
BRN	110960
InChI	InChI=1S/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3
InChIKey	ILRVKOYYFFNXDB-UHFFFAOYSA-N
SMILES	C(C1C=CN=CC=1)C(=O)C
CAS DataBase Reference	6304-16-1(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
ALFA	English

4-Pyridyl acetone Usage And Synthesis

Description	1-(4-pyridyl)acetone is a yellow liquid, which is a key intermediate for synthesizing cardiac drug Milrinone.
Preparation	4-Pyridyl acetone can be prepared by reacting with 4-picoline and phenyllithium and ethyl acetate.
Physical properties	4-pyridyl acetone is a Light yellow to yellow liquid.
Chemical Properties	Liquid. Boiling point 130-132℃/1.5kPa.
Uses	(4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.
Synthesis Reference(s)	Tetrahedron Letters, 25, p. 3297, 1984 DOI: 10.1016/S0040-4039(01)81368-X

4-Pyridyl acetone Preparation Products And Raw materials

Raw materials	Ethanol-->Ethyl acetate-->Tetrahydrofuran-->Acetic acid-->Petroleum ether-->Chloroform-->n-Butyllithium-->Diisopropylamine-->Hexamethylphosphoramide-->4-Methylpyridine-->Phenyllithium-->N-methoxy-N-methyl-2-(pyridin-4-yl)acetamide-->4-Pyridineacetic acid hydrochloride-->Propyl acetate-->Methyl acetate-->Acetyl chloride-->Methylmagnesium Bromide-->Pyridine
Preparation Products	Milrinone

Tag:4-Pyridyl acetone(6304-16-1) Related Product Information

Benzenesulfonyl chloride Trifluoromethanesulfonic acid Pyrazine 4-Pyridyl acetone Acetone 1-(4-Chloro-phenyl)-2-pyridin-4-yl-ethanone 1-Phenyl-2-pyridin-4-yl-ethanone 2-Pyridin-4-yl-1-(4-trifluoromethyl-phenyl)-ethanone 2-Pyridin-4-yl-1-p-tolyl-ethanone 1-(4-Fluoro-phenyl)-2-pyridin-4-yl-ethanone 3-Hydroxy-2-pyridin-4-yl-inden-1-one 2-Quinolin-4-yl-1-[4-(trifluoromethyl)phenyl]ethanone 1-(4-Methoxy-phenyl)-2-pyridin-4-yl-ethanone 2-(9-Acridinyl)-1-phenylethanone 2-(4-Pyridyl)indane-1,3-dione 4-Pyridinyl[3-(trifluoromethyl)phenyl]-ethanedione RARECHEM AK HZ 0058