2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)-

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2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Suppliers list
Company Name: Suzhou Meishi Biotechnology Co., Ltd.  
Tel: 1173954148q
Email: meishipharma@126.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Shandong Ziyi Pharmaceutical Co., Ltd.  
Tel: 17860786593
Email: 1181917242@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- manufacturers

  • F15845
  • F15845 pictures
  • $2880.00
  • 2026-05-21
  • CAS:470454-73-0
  • Purity:
  • Supply Ability: 10g
2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Basic information
Product Name:2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)-
Synonyms:2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)-;F15845;(R)-N-((S)-3-((2-methoxyphenyl)thio)-2-methylpropyl)-3,4-dihydro-2H-benzo[b][1,4]oxathiepin-3-amine
CAS:470454-73-0
MF:C20H25NO2S2
MW:375.55
EINECS:
Product Categories:
Mol File:470454-73-0.mol
2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Structure
2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Chemical Properties
Safety Information
MSDS Information
2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Usage And Synthesis
UsesF 15845 is a highly effective persistent sodium current blocker. F 15845 also is a cardioprotective agent, has anti-ischemic activity and exerts short- and long-term cardioprotection after myocardial infarction. F 15845 can be used for the research of myocardium functional impairment[1].
in vivo

F 15845 (i.v.; 5 mg/kg) exhibits remarkable cardioprotective properties in anesthetized rat[1].

Animal Model:Rat[1]
Dosage:2.5 mg/kg, 5 mg/kg
Administration:intravenously
Result:Significantly reduced infarct size, decreased of troponin I levels and limited the long-term expansion of infarct size.
References[1] Bruno Vié, et al. 3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload. J Pharmacol Exp Ther. 2009 Sep;330(3):696-703. DOI:10.1124/jpet.109.153122
2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)- Preparation Products And Raw materials
Tag:2H-1,5-Benzoxathiepin-3-amine, 3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-, (3R)-(470454-73-0) Related Product Information
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