| Company Name: |
Accela ChemBio Inc. |
| Tel: |
+1-858-6993322 +86-18019713315 |
| Email: |
info@accelachem.com |
| Company Name: |
csynbio |
| Tel: |
15051477682 |
| Email: |
changming.pan@csynbio.com |
|
| | VH032-C10-NH2 Basic information |
| Product Name: | VH032-C10-NH2 | | Synonyms: | VH032-C10-NH2;(S,R,S)-AHPC-C10-NH2;PROTACs Related Compound 5;L-Prolinamide, N-(11-amino-1-oxoundecyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2);S)-AHPC-C10-NH2;PROTAC,(S,R,S) AHPC C10 NH2,Inhibitor,(S,R,S)AHPCC10NH2,E3 Ligase Ligand-Linker Conjugates,AHPC,(S,R,S)-AHPC-C-10-NH2,BET,VHL,inhibit;(2S,4R)-1-((S)-2-(11-Aminoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | | CAS: | 2341796-74-3 | | MF: | C33H51N5O4S | | MW: | 613.85 | | EINECS: | | | Product Categories: | | | Mol File: | 2341796-74-3.mol |  |
| | VH032-C10-NH2 Chemical Properties |
| Boiling point | 852.5±65.0 °C(Predicted) | | density | 1.156±0.06 g/cm3(Predicted) | | pka | 14.08±0.40(Predicted) |
| | VH032-C10-NH2 Usage And Synthesis |
| Uses | (S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC[1]. | | IC 50 | VHL | | References | [1] Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31. DOI:10.1002/cmdc.201900497 |
| | VH032-C10-NH2 Preparation Products And Raw materials |
|