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| | Magnesium dipropylacetate hydrate Basic information |
| Product Name: | Magnesium dipropylacetate hydrate | | Synonyms: | Bis(2-propylpentanoic acid)magnesium salt;Einecs 263-770-9;Pentanoic acid, 2-propyl-, magnesium salt;MAGNESIUM DIPROPYLACETATE;MAGNESIUM VALPROATE HYDRATE;2-propyl-pentanoicacimagnesiumsalt;magnesium 2-propylvalerate;Valproic acid, magnesium salt | | CAS: | 62959-43-7 | | MF: | C16H30MgO4 | | MW: | 310.71 | | EINECS: | 263-770-9 | | Product Categories: | API | | Mol File: | 62959-43-7.mol |  |
| | Magnesium dipropylacetate hydrate Chemical Properties |
| Melting point | >294°C (dec.) | | storage temp. | Refrigerator | | solubility | Ethyl Acetate (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White | | InChI | InChI=1S/2C8H16O2.Mg/c2*1-3-5-7(6-4-2)8(9)10;/h2*7H,3-6H2,1-2H3,(H,9,10);/q;;+2/p-2 | | InChIKey | LKLLHOIUJVEAGU-UHFFFAOYSA-L | | SMILES | C(CCC)(CCC)C(=O)O[Mg]OC(=O)C(CCC)CCC | | CAS DataBase Reference | 62959-43-7 |
| | Magnesium dipropylacetate hydrate Usage And Synthesis |
| Uses | Magnesium Valproate is an anticonvulsant agent and the effects it exerts are the result of valproic acid and magnesium acting in a complementary way. Magnesium valproate is effective as monotherapy in patients with newly diagnosed or previously treated partial or generalised epilepsy. | | Uses | Antiepileptic | | Trade name | Logical (Armstrong) | | Safety Profile | Moderately toxic by
ingestion. Danger: A spontaneously
combustible solid. When heated to
decomposition it emits toxic vapors of
magnesium. | | Synthesis |
Diethyl malonate is alkylated with 1-bromopropane and then hydrolyzed and decarboxylated to afford Magnesium valproate.
| | Description | Valproic acid and its salt Magnesium Valproate is major antiepileptic drugs for the treatment of absence, myoclonic, and generalized tonic – clonic seizures and also may be effective against complex partial seizures. The most cited mechanisms are the increase in GABA function and the blockade of voltage-dependent Na+-channels. The most common side effects are gastrointestinal disturbances and sedation. The most serious adverse effect is liver damage, although this is rare. Teratogenic effects, predominantly spina bifida, are reported frequently. |
| | Magnesium dipropylacetate hydrate Preparation Products And Raw materials |
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