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| | SRI-43265 Basic information |
| Product Name: | SRI-43265 | | Synonyms: | SRI-43265;Imidazo[1,2-b]pyridazin-6-amine, 3-(1H-indazol-5-yl)-N-methyl-N-(tetrahydro-2H-pyran-4-yl)- | | CAS: | 2727872-88-8 | | MF: | C19H20N6O | | MW: | 348.4 | | EINECS: | | | Product Categories: | | | Mol File: | 2727872-88-8.mol |  |
| | SRI-43265 Chemical Properties |
| density | 1.441±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.819±0.10(predicted) | | form | Solid | | color | Off-white to light yellow |
| | SRI-43265 Usage And Synthesis |
| Uses | SRI-43265 (compound 40) is an inhibitor of human antigen R protein (HuR) dimerization, and HuR multimers have been implicated in cancer and inflammatory pathogenesis[1]. | | References | [1] Preparation of imidazopyridazinamines as RNA-binding protein multimerization inhibitors and methods of use thereof. World Intellectual Property Organization, WO2021216757 A1 2021-10-28. |
| | SRI-43265 Preparation Products And Raw materials |
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