- Corylin
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- $60.00 / 1mL
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2026-03-13
- CAS:53947-92-5
- Min. Order:
- Purity: 98.44%
- Supply Ability: 10g
- Corylin
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- $0.00 / 20mg
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2023-02-24
- CAS:53947-92-5
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Corylin
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- $1.00 / 1kg
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2019-07-06
- CAS:53947-92-5
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
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| | Corylin Basic information |
| Product Name: | Corylin | | Synonyms: | Corylin;7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one;4H-1-Benzopyran-4-one, 3-(2,2-dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-;3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one;7-Hydroxy-2',2'-dimethyl-2'H,4H-[3,6'-bichromen]-4-one;Corylin-RM;Corylin, 10 mM in DMSO | | CAS: | 53947-92-5 | | MF: | C20H16O4 | | MW: | 320.34 | | EINECS: | | | Product Categories: | | | Mol File: | 53947-92-5.mol |  |
| | Corylin Chemical Properties |
| Melting point | 238-239 °C(Solv: acetone (67-64-1); hexane (110-54-3)) | | Boiling point | 527.4±50.0 °C(Predicted) | | density | 1.295±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO : ≥ 100 mg/mL (312.17 mM);Water : < 0.1 mg/mL (insoluble) | | form | powder | | pka | 6.98±0.20(Predicted) | | color | Yellowish | | InChI | InChI=1S/C20H16O4/c1-20(2)8-7-13-9-12(3-6-17(13)24-20)16-11-23-18-10-14(21)4-5-15(18)19(16)22/h3-11,21H,1-2H3 | | InChIKey | PWAACAMQKVIVPZ-UHFFFAOYSA-N | | SMILES | C1OC2=CC(O)=CC=C2C(=O)C=1C1C=C2C(=CC=1)OC(C)(C)C=C2 | | CAS DataBase Reference | 53947-92-5 |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Corylin Usage And Synthesis |
| Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Psoralea fruit. | | Uses | Corylin has anti-inflammatory, anti-viral, anti-aging, anti-bacterial and anti-tumor effects. | | Biological Activity | Corylin is an important biologically active compound isolated from Psoralea; antibiotic or anticancer compound. | | in vivo | Corylin (60 mg/kg, i.p., three times a week, 4 weeks) inhibits tumor growth in Huh7 cells xenograft mice[3].
Corylin (50-100 mg/kg, p.o., daily, 9 weeks) improves the high-fat diet (HFD)-induced obesity in HFD- and DIO-treated mice[3].
| Animal Model: | HFD- and DIO-treated mice[3] | | Dosage: | 50-100 mg/kg | | Administration: | Oral gavage (p.o.), daily, 9 weeks | | Result: | Reduced the weight of subcutaneous, visceral WAT, and body.
Decreased the size of WAT adipocyte.
Increased insulin sensitivity, mitochondrial biogenesis, and β-oxidation.
Reduced serum levels of insulin and leptin and improved HOMA-IR.
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| | Corylin Preparation Products And Raw materials |
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