| Company Name: |
BePharm Ltd |
| Tel: |
400-685-9117 |
| Email: |
market@bepharm.com |
1-Bromo-2-ethyl-4-methoxy-benzene manufacturers
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| | 1-Bromo-2-ethyl-4-methoxy-benzene Basic information |
| | 1-Bromo-2-ethyl-4-methoxy-benzene Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature | | Appearance | Colorless to light yellow Liquid |
| | 1-Bromo-2-ethyl-4-methoxy-benzene Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 1-bromo-2-ethyl-4-methoxybenzene from 1-ethyl-3-methoxybenzene: 3-ethylanisole (50 g, 0.3676 mol) and N-bromosuccinimide (72 g, 0.4 mol) were dissolved in acetonitrile (1 L), and the reaction was stirred for 8 hours at room temperature protected from light. After completion of the reaction, the reaction mixture was concentrated at a temperature below 40 °C. The concentrated residue was redissolved in carbon tetrachloride and filtered to remove insoluble material. The filtrate was concentrated and finally the target product was obtained by fractional purification. A light yellow liquid product of 35 g was obtained in 43% yield. | | References | [1] Bulletin of the Chemical Society of Japan, 1989, vol. 62, # 2, p. 591 - 593
[2] Patent: US2006/4222, 2006, A1. Location in patent: Page/Page column 1; 3; 5
[3] Journal of Medicinal Chemistry, 2009, vol. 52, # 23, p. 7788 - 7799 |
| | 1-Bromo-2-ethyl-4-methoxy-benzene Preparation Products And Raw materials |
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