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Thromboxane B2

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Thromboxane B2 Basic information
Product Name:Thromboxane B2
Synonyms:9ALPHA,11,15S-TRIHYDROXYTHROMBA-5Z,13E-DIEN-1-OIC ACID;[5Z,9ALPHA,11RS,13E,15S]-9,11,15-TRIHYDROXYTHROMBOXA-5,13-DIEN-1-OIC ACID;(5z,9α,11rs,13e,15s)-9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid;(E)-7-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid;TXB2, (5Z,9α,11RS,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid;(5Z,13E,15S)-9α,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid;(5Z,9α,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-diene-1-oic acid;Thromboxane B2 EIA
CAS:54397-85-2
MF:C20H34O6
MW:370.48
EINECS:
Product Categories:Fatty Acid Derivatives & Lipids;Glycerols;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:54397-85-2.mol
Thromboxane B2 Structure
Thromboxane B2 Chemical Properties
Melting point 95-96°
alpha D25 +57.4° (c = 0.26 in ethyl acetate)
storage temp. −20°C
solubility Chloroform (Slightly, Heated)
form Solid
color White to Off-White
Merck 13,9466
Safety Information
Hazard Codes Xn,T
Risk Statements 63-52/53-34-32-23/24/25-5
Safety Statements 22-36-45-36/37/39-26
WGK Germany 3
8-10-21
MSDS Information
Thromboxane B2 Usage And Synthesis
Chemical PropertiesWhite Solid
UsesAn inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
UsesTXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
DefinitionChEBI: A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
Thromboxane B2 Preparation Products And Raw materials
Tag:Thromboxane B2(54397-85-2) Related Product Information
Thrombospondin 1 (A6.1) Alexa Fluor? 594 Thrombospondin 2 (4) Thrombospondin-1 (D7E5F) Rabbit mAb Thrombospondin 1 (A6.1) Thrombospondin 4 (G-10) 9alpha, 11, 15S-trihydroxy-thromba-5z, 13e, 17z-trien-1-oic acid THROMBOXANE A2 Thromboxane-A Synthase THROMBOXANE SYNTHASE BLOCKING PEPTIDE 11-Dehydro thromboxane B2 Thromboxane B2 11-Dehydro thromboxane B2-d4 9alpha,11,15S-trihydroxy-thromba-5z,13e-dien-1-oic-3,3,4,4-d4 acid 3-Hexene-2,5-diol 11-Dehydro thromboxane B3 9alpha,11alpha-Methylene-15s-hydroxy-11a-deoxy-11a-methylene-thromba-5z,13e-dien-1-oic acid Pinane thromboxane A2 9alpha,11,15S-trihydroxy-thrombox-13e-en-1-oic acid