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| | Z-Val-Ala-Asn-AMC Basic information |
| Product Name: | Z-Val-Ala-Asn-AMC | | Synonyms: | Z-VAN-AMC;L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (9CI);Z-Val-Ala-Asn-AMC | | CAS: | 245036-58-2 | | MF: | C30H35N5O8 | | MW: | 593.63 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | Z-Val-Ala-Asn-AMC Chemical Properties |
| Boiling point | 976.481±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.309±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -15°C | | pka | 11.050±0.46(predicted) | | Sequence | Z-Val-Ala-Asn-{AMC} |
| | Z-Val-Ala-Asn-AMC Usage And Synthesis |
| Uses | Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity[1][2]. | | References | [1] Timo Burster, et al. Cathepsin G, and Not the Asparagine-Specific Endoprotease, Controls the Processing of Myelin Basic Protein in Lysosomes from Human B Lymphocytes1. J Immunol 1 May 2004; 172 (9): 5495–5503. [2] Santamaría ME, et al. Digestive proteases in bodies and faeces of the two-spotted spider mite, Tetranychus urticae. J Insect Physiol. 2015 Jul;78:69-77. DOI:10.1016/j.jinsphys.2015.05.002 |
| | Z-Val-Ala-Asn-AMC Preparation Products And Raw materials |
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