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| | (R)-TERT-LEUCINOL Basic information |
| Product Name: | (R)-TERT-LEUCINOL | | Synonyms: | (R)-(-)-TERT-LEUCINOL;(R)-TERT-LEUCINOL;(R)-2-AMINO-3,3-DIMETHYL-1-BUTANOL;H-D-TLE-OL;H-D-(TBU)GLY-OL;D-ALPHA-T-BUTYLGLYCINOL;D-T-LEUCINOL;D-T-BUTYLGLYCINOL | | CAS: | 112245-09-7 | | MF: | C6H15NO | | MW: | 117.19 | | EINECS: | | | Product Categories: | | | Mol File: | 112245-09-7.mol |  |
| | (R)-TERT-LEUCINOL Chemical Properties |
| Melting point | 30-33 °C(lit.) | | Boiling point | 70 °C0.4 mm Hg(lit.) | | density | 0.9 g/mL at 25 °C(lit.) | | Fp | 194 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | form | Liquid | | pka | 12.88±0.10(Predicted) | | color | Colorless to yellow | | Optical Rotation | [α]20/D 37°, c = 1.5 in ethanol | | Major Application | peptide synthesis | | InChI | InChI=1S/C6H15NO/c1-6(2,3)5(7)4-8/h5,8H,4,7H2,1-3H3/t5-/m0/s1 | | InChIKey | JBULSURVMXPBNA-YFKPBYRVSA-N | | SMILES | C(O)[C@H](N)C(C)(C)C |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2922190090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | (R)-TERT-LEUCINOL Usage And Synthesis |
| Uses | (R)-Tert-leucinol (H-D-Tle-ol) is a chiral molecular compound with optical activity and its enantiomeric form is (S)-tert-leucinol. (R)-Tert-leucinol belongs to the class of α-amino alcohols, which have certain biological activities and are potent reversible inhibitors of protein synthesis. (R)-Tert-leucinol can be used as a chiral ligand for asymmetric catalytic reactions. Its derivatives are also used as optical splitting reagents, for peptidyl alcohol synthesis in peptide drugs, and as inhibitors of protein hydrolysis. | | reaction suitability | reaction type: solution phase peptide synthesis |
| | (R)-TERT-LEUCINOL Preparation Products And Raw materials |
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