(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine

(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine Suppliers list

Company Name:	Shanghai Holy Biohemdeviser Co., Ltd
Tel:	021-61551100
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(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine Basic information

Product Name:	(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine
Synonyms:	(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDINE-2-YL)-METHYL]-PYRROLIDINE;(-)-2-HYDROXYMETHYL-(1-METHYLPYRROLIDIN- 2-YLME)PYRROLIDINE;2-hydroxymethyl-(1-methylpyrrolidin-2ylmethyl)pyrrolidine;(2S,2S)-1-(1-Methyl-2-pyrrolidinylmethyl)pyrrolidine-2-methanol;(2S,2''S)-(-)-2-HYDROXYMETHYL-1-[(1-METHY;2-PyrrolidineMethanol,1-[[(2S)-1-Methyl-2-pyrrolidinyl]Methyl]-, (2S)-;(1-((1-Methylpyrrolidin-2-yl)methyl)pyrrolidin-2-yl)methanol;(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine
CAS:	66283-23-6
MF:	C11H22N2O
MW:	198.31
EINECS:
Product Categories:
Mol File:	66283-23-6.mol

(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine Chemical Properties

Boiling point	275-277 °C
alpha	[α]28D -130° (c 0.36, EtOH)
density	1.034±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
refractive index	n20/D 1.494
solubility	sol hexane, toluene, Me2O, Et2O, n-Pr2O, THF, dimethoxymethane.
pka	14.773±0.10(predicted)

Safety Information

MSDS Information

(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine Usage And Synthesis

Uses	(2S,2′S)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine is a chiral ligand for alkyllithium, dialkylmagnesium, alkynyllithium, and functionalized organolithiums in the enantioselective addition to aldehydes; accelerates the basicity of alkyllithiums; catalyzes the addition of dialkylzinc to aldehyde.
Preparation	Preparative Method of (2S,2′S)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine: reduction of N-[N(-benzyloxycarbonyl)prolyl]proline methyl ester with Lithium Aluminum Hydride affords the title reagent in 81% yield.

(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine Preparation Products And Raw materials

Tag:(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)-methyl]-pyrrolidine(66283-23-6) Related Product Information

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