3-Isoxazolemethanol

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CAS:89102-73-8
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CAS:89102-73-8
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CAS:89102-73-8
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Products Intro: Product Name:3-Isoxazolemethanol
CAS:89102-73-8
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  • 3-Isoxazolemethanol
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  • $200.00 / 1KG
  • 2025-09-25
  • CAS:89102-73-8
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  • Purity: 99%, 99.5% Sublimated
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  • 3-Isoxazolemethanol
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  • $0.00 / 1KG
  • 2020-01-01
  • CAS:89102-73-8
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 200kg
3-Isoxazolemethanol Basic information
Product Name:3-Isoxazolemethanol
Synonyms:ISOXAZOL-3-YLMETHANOL;3-hydroxymethylisoxazole;AKOS PAO-1430;3-ISOXAZOLEMETHANOL;1,2-oxazol-3-ylMethanol
CAS:89102-73-8
MF:C4H5NO2
MW:99.09
EINECS:
Product Categories:
Mol File:89102-73-8.mol
3-Isoxazolemethanol Structure
3-Isoxazolemethanol Chemical Properties
Boiling point 240.0±15.0 °C(Predicted)
density 1.250±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
form liquid
pka13.11±0.10(Predicted)
color Light Yellow
InChI1S/C4H5NO2/c6-3-4-1-2-7-5-4/h1-2,6H,3H2
InChIKeyGBCAGXLDCTZCCT-UHFFFAOYSA-N
SMILESOCC1=NOC=C1
Safety Information
WGK Germany WGK 3
HS Code 2905190098
Storage Class11 - Combustible Solids
MSDS Information
3-Isoxazolemethanol Usage And Synthesis
Synthesis
Isoxazole-3-carbaldehyde

89180-61-0

3-Isoxazolemethanol

89102-73-8

General procedure for the synthesis of 3-hydroxymethylisoxazole from 3-formylisoxazole: 0.039 g (1.03 mmol) of sodium borohydride was dissolved in a solvent mixture of 4 mL of tetrahydrofuran and 0.13 mL of methanol and cooled in an ice bath under conditions of 0°C to 5°C. Subsequently, 1 mL of tetrahydrofuran solution containing 0.100 g (1.03 mmol) of 3-formylisoxazole was added dropwise to this solution. The reaction mixture was stirred at room temperature for 16 hours and then concentrated by rotary evaporator. The concentrated residue was separated by extraction with water and ethyl acetate. The organic phase was washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and evaporated to dryness again by rotary evaporator. Finally 0.110 g of 3-hydroxymethylisoxazole was obtained in a yield of 100% of the theoretical value.

References[1] Patent: US2006/116372, 2006, A1. Location in patent: Page/Page column 7
3-Isoxazolemethanol Preparation Products And Raw materials
Raw materialsEthyl propiolate-->Isoxazole-3-carbaldehyde-->Water-->Methanol-->Sodium borohydride-->Tetrahydrofuran-->Ethyl acetate
Tag:3-Isoxazolemethanol(89102-73-8) Related Product Information
Oxymetazoline 5-ETHYL-ISOXAZOLE-3,4-DICARBOXYLIC ACID DIETHYL ESTER ETHYL 5-METHYLISOXAZOLE-3-CARBOXYLATE (5-Methylisoxazol-3-yl)methanol 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID Oxymetazoline hydrochloride ETHYL 5-(2-BROMOACETYL)ISOXAZOLE-3-CARBOXYLATE Methyl 5-methylisoxazole-3-carboxylate 5-ISOXAZOLEMETHANOL 3,5-Dimethyl-4-isoxazolemethanol 3-(4-NITRO-PHENYL)-ISOXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER ETHYL 4-(4-BROMOBENZOYL)-3-ISOXAZOLECARBOXYLATE ETHYL 5-ACETYLISOXASOLE-3-CARBOXYLATE METHYL 4-(1-HYDROXYIMINOETHYL)-5-METHYLISOXAZOLE-3-CARBOXYLATE METHYL 4-ACETYL-5-METHYLISOXAZOLE-3-CARBOXYLATE METHYL 6-NITRO-1,2-BENZISOXAZOLE-3-CARBOXYLATE ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE 4-Isoxazolemethanol,3-(4-methoxyphenyl)-5-methyl-(9CI)

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