- N3-PEG3-Boc-NH
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2026-07-24
- CAS:642091-68-7
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG3-NHBoc
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2025-06-07
- CAS:642091-68-7
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Azido-PEG4-NHBoc Basic information |
| Product Name: | Azido-PEG4-NHBoc | | Synonyms: | Azido-PEG4-NHBoc;t-Boc-N-Amido-PEG3-Azide;Boc-N-Amido-PEG3-Azide;tert-Butyl N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)carbamate;BocNH-PEG3-CH2CH2N3;Boc-NH-PEG3-N3;N3-PEG3-NH-BOC;tert-butyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate | | CAS: | 642091-68-7 | | MF: | C13H26N4O5 | | MW: | 318.38 | | EINECS: | | | Product Categories: | SiChem;peg | | Mol File: | 642091-68-7.mol |  |
| | Azido-PEG4-NHBoc Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Azido-PEG4-NHBoc Usage And Synthesis |
| Description | t-Boc-N-Amido-PEG3-azide is a PEG reagent containing an azide group and Boc-protected amino group, it is reactive with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Uses | Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-N-Amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | Definition | ChEBI: Tert-Butyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate is a carbamate ester. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG4-NHBoc Preparation Products And Raw materials |
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